SCHEMBL13370622

SCHEMBL13370622

COC(=O)CC1C(CC(=O)OC)C2CC1C1C3C=CC(C3)C21

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ TSHR P16473 1/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13346322 0.94 MEN1 (0.32) PKMSMN1; SMN2TSHRMEN1KMT2A
SCHEMBL13346309 0.91 PKM (0.32) PKMSMN1; SMN2
SCHEMBL13346324 0.88 MEN1 (0.39) PKMSMN1; SMN2TSHRMEN1KMT2A
SCHEMBL13346304 0.83 SMN1; SMN2 (0.39) PKMSMN1; SMN2TSHRMEN1KMT2A
SCHEMBL13346372 0.80 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL13346327 0.79 TSHR (0.35) PKMSMN1; SMN2TSHR
SCHEMBL13346679 0.78 HSD11B1 (0.41) SMN1; SMN2
SCHEMBL13066330 0.78 PKM (0.32) PKMSMN1; SMN2
SCHEMBL13895236 0.77 PKM (0.36) PKMSMN1; SMN2TSHRMEN1KMT2A
SCHEMBL13346280 0.77 MEN1 (0.36) PKMSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7714087-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2010-05-11 — — US disclosed
EP-1734061-B1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof MITSUI CHEMICALS INC (JP) 2010-04-07 — — EP disclosed
US-20090137757-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof IMUTA JUNICHI 2009-05-28 — — US disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 — — US disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 — — US disclosed
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