SCHEMBL13346679

SCHEMBL13346679

O=C(O)CC1C(CC(=O)O)C2CC1C1C3C=CC(C3)C21

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 1/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ MAPK1 P28482 1/20 0.35
▸ SLC6A12 P48065 4/20 0.34
▸ SLC6A11 P48066 4/20 0.34
▸ SLC6A13 Q9NSD5 4/20 0.34
▸ POLB P06746 3/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33
▸ GABRA1 P14867 1/20 0.32
▸ GABRR1 P24046 1/20 0.32
▸ SLC6A1 P30531 1/20 0.32
▸ GABRA5 P31644 1/20 0.32
▸ GABRB2 P47870 1/20 0.32
▸ GABRA4 P48169 1/20 0.32
▸ APEX1 P27695 1/20 0.31
▸ MCL1 Q07820 3/20 0.31
▸ BCL2L1 Q07817 2/20 0.31
▸ ALDH1A1 P00352 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13346672 0.91 SMN1; SMN2 (0.36) HSD11B1SMN1; SMN2L3MBTL1MAPK1ALDH1A1
SCHEMBL13346678 0.90 MAPK1 (0.36) HSD11B1SMN1; SMN2L3MBTL1MAPK1MCL1
SCHEMBL13346677 0.89 POLB (0.41) HSD11B1SMN1; SMN2L3MBTL1POLBTDP1
SCHEMBL13346666 0.88 SMN1; SMN2 (0.36) HSD11B1SMN1; SMN2L3MBTL1MAPK1
SCHEMBL13346372 0.82 SMN1; SMN2 (0.33) SMN1; SMN2L3MBTL1POLBTDP1APEX1
SCHEMBL13346526 0.82 RAB9A (0.39) SMN1; SMN2L3MBTL1
SCHEMBL5848235 0.81 HSD11B1 (0.48) HSD11B1SMN1; SMN2L3MBTL1MAPK1SLC6A12
SCHEMBL13370622 0.78 PKM (0.35) SMN1; SMN2
SCHEMBL13370540 0.77 — —
SCHEMBL14117817 0.75 RAB9A (0.34) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7714087-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2010-05-11 — — US disclosed
US-7714087-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2010-05-11 — — US disclosed
US-20090137757-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof IMUTA JUNICHI 2009-05-28 — — US disclosed
US-20090137757-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof IMUTA JUNICHI 2009-05-28 — — US disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 — — US disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 — — US disclosed
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