Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | UTRN | P46939 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11649131 | 0.89 | KDM4E (0.47) | ALDH1A1KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL13866097 | 0.89 | RAB9A (0.46) | ALDH1A1KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL30129872 | 0.89 | RAB9A (0.46) | ALDH1A1KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL23630624 | 0.79 | MAPT (0.54) | ALDH1A1KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL29859231 | 0.79 | MAPT (0.54) | ALDH1A1KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL8995192 | 0.79 | GPR119 (0.43) | HSD17B10MEN1KMT2AUTRNCASP3 | |
| SCHEMBL20052138 | 0.78 | MEN1 (0.41) | ALDH1A1KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL23630617 | 0.76 | MAPT (0.62) | ALDH1A1KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL29859543 | 0.76 | MAPT (0.61) | ALDH1A1KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL23630613 | 0.76 | MAPT (0.61) | ALDH1A1KDM4EHSD17B10HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723412-B2 | Stabilization of thermoplastic nanocomposites | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| EP-1592741-B1 | STABILIZATION OF THERMOPLASTIC NANOCOMPOSITES | CIBA HOLDING INC (CH) | 2009-01-14 | — | — | EP | disclosed |