Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815915 | 0.91 | ALDH1A1 (0.56) | ALDH1A1HPGDMAPTTSHRALOX15 | |
| SCHEMBL8153001 | 0.83 | RAB9A (0.62) | ALDH1A1HPGDMAPTTSHRALOX15 | |
| SCHEMBL8153005 | 0.83 | RAB9A (0.62) | ALDH1A1HPGDMAPTTSHRALOX15 | |
| SCHEMBL8184701 | 0.83 | RAB9A (0.62) | ALDH1A1HPGDMAPTTSHRALOX15 | |
| SCHEMBL13372976 | 0.80 | MAPT (0.46) | ALDH1A1HPGDMAPTTSHRALOX15 | |
| SCHEMBL9313917 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTTSHRALOX15 | |
| SCHEMBL8994723 | 0.79 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTTSHRALOX15 | |
| SCHEMBL14488623 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTTSHRALOX15 | |
| SCHEMBL6937372 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HPGDMAPTTSHRALOX15 | |
| SCHEMBL10680528 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTTSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8287767-B2 | Amorphous polymers with pendant chromogenic groups | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-10-16 | — | — | US | disclosed |