Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.45 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680531 | 0.87 | QPCT (0.60) | MAPK14IDO1METAP2QPCTQPCTL | |
| SCHEMBL13373486 | 0.84 | PARP1 (0.46) | QPCTQPCTLMAP3K8BRD4CREBBP | |
| SCHEMBL6008269 | 0.84 | MAPT (0.50) | QPCTQPCTLBRD4CREBBP | |
| SCHEMBL31143361 | 0.84 | MAPT (0.50) | QPCTQPCTLBRD4CREBBP | |
| SCHEMBL22418755 | 0.83 | QPCT (0.47) | QPCTQPCTL | |
| SCHEMBL2457365 | 0.82 | QPCT (0.50) | QPCTQPCTL | |
| SCHEMBL28178103 | 0.80 | IDO1 (0.50) | IDO1METAP2QPCTQPCTL | |
| SCHEMBL29908926 | 0.80 | PARP1 (0.56) | QPCTBRD4CREBBP | |
| SCHEMBL15413217 | 0.80 | PARP1 (0.56) | QPCTBRD4CREBBP | |
| SCHEMBL10903 | 0.80 | PARP1 (0.56) | QPCTBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |