Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 6/20 | 0.60 |
| ▸ | QPCTL | Q9NXS2 | 5/20 | 0.60 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13373333 | 0.87 | MAPK14 (0.47) | QPCTQPCTLMAP3K8BRD4CREBBP | |
| SCHEMBL15638693 | 0.84 | QPCT (0.51) | QPCTQPCTLMAP3K8BRD4CREBBP | |
| SCHEMBL8634290 | 0.84 | QPCT (0.68) | QPCTQPCTLBRD4CREBBPKDM4E | |
| SCHEMBL22418756 | 0.83 | QPCT (0.64) | QPCTQPCTLKDM4ENPC1ALDH1A1 | |
| SCHEMBL2462345 | 0.82 | QPCT (0.68) | QPCTQPCTLBRD4CREBBPKDM4E | |
| SCHEMBL23227938 | 0.80 | QPCT (0.60) | QPCTQPCTLBRD4CREBBPKDM4E | |
| SCHEMBL29804755 | 0.80 | QPCT (0.60) | QPCTQPCTLKDM4ENPC1ALDH1A1 | |
| SCHEMBL29804939 | 0.80 | QPCT (0.60) | QPCTQPCTLBRD4CREBBPKDM4E | |
| SCHEMBL23227763 | 0.80 | QPCT (0.60) | QPCTQPCTLKDM4ENPC1ALDH1A1 | |
| SCHEMBL28178104 | 0.80 | QPCT (0.60) | QPCTQPCTLBRD4CREBBPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |