Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240523 | 0.86 | MTNR1A (0.54) | MTNR1AMTNR1BFLT3MAPK1 | |
| SCHEMBL11243423 | 0.86 | MTNR1A (0.54) | MTNR1AMTNR1BFLT3MAPK1 | |
| SCHEMBL11222659 | 0.82 | MTNR1A (0.49) | MTNR1AMTNR1BCA1CA2CA12 | |
| SCHEMBL2827572 | 0.72 | DAPK3 (0.49) | MTNR1AMTNR1BPIM1FLT3MAPK1 | |
| SCHEMBL19768747 | 0.71 | KMT2A (0.42) | PIM1FLT3 | |
| SCHEMBL25590503 | 0.71 | KDM5A (0.38) | MTNR1AMTNR1BMAPK1 | |
| SCHEMBL8167570 | 0.70 | CA1 (0.44) | MTNR1AMTNR1BCA1CA2CA12 | |
| SCHEMBL12777459 | 0.70 | CA1 (0.44) | MTNR1AMTNR1BCA1CA2CA12 | |
| SCHEMBL1029693 | 0.70 | MTNR1A (0.77) | MTNR1AMTNR1BCA1CA2CA12 | |
| SCHEMBL30595323 | 0.70 | MTNR1A (0.77) | MTNR1AMTNR1BCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |