SCHEMBL133738

SCHEMBL133738

O=C(CSCC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.87
KMT2A Q03164 4/20 0.61
HPGD P15428 4/20 0.61
CYP3A4 P08684 4/20 0.61
MAPK1 P28482 3/20 0.61
MAPT P10636 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
MEN1 O00255 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
KDM4E B2RXH2 2/20 0.61
ALOX15 P16050 1/20 0.61
CES1 P23141 1/20 0.61
HIF1A Q16665 3/20 0.56
GSK3B P49841 2/20 0.56
PTPN1 P18031 2/20 0.56
TRPA1 O75762 1/20 0.56
RAB9A P51151 4/20 0.55
L3MBTL1 Q9Y468 2/20 0.54
LMNA P02545 1/20 0.54
NR4A2 P43354 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2874180 0.93 ALDH1A1 (1.00) ALDH1A1KMT2AHPGDCYP3A4MAPK1
SCHEMBL9000687 0.91 ALDH1A1 (0.74) ALDH1A1KMT2AHPGDCYP3A4MAPK1
SCHEMBL1581464 0.87 ALDH1A1 (0.68) ALDH1A1KMT2AHPGDCYP3A4MAPK1
SCHEMBL5031039 0.85 ALDH1A1 (0.65) ALDH1A1KMT2AHPGDCYP3A4MAPK1
SCHEMBL824471 0.85 ALDH1A1 (0.66) ALDH1A1KMT2AHPGDCYP3A4MAPK1
SCHEMBL8229602 0.85 ALDH1A1 (0.66) ALDH1A1KMT2AHPGDCYP3A4MAPK1
SCHEMBL20707338 0.83 ALDH1A1 (0.63) ALDH1A1KMT2AHPGDCYP3A4MAPK1
SCHEMBL6270890 0.83 ALDH1A1 (0.63) ALDH1A1KMT2AHPGDMAPTSMN1; SMN2
SCHEMBL6683314 0.83 ALDH1A1 (0.63) ALDH1A1KMT2AHPGDCYP3A4MAPK1
SCHEMBL10886619 0.82 KMT2A (0.64) ALDH1A1KMT2AHPGDCYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988662-A MULTILAYER ELEMENT OF A COATED SUBSTRATE, A FILM WITH A COLOR-FORMING LACTONE, AN ACID AND A SENSITIZER DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-01-29 US claimed
JP-2029382-A None JP disclosed
US-20240049386-A1 LAMINATE AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2024-02-08 US disclosed
CN-117465091-A Laminate and electronic device 富士胶片株式会社 2024-01-30 CN disclosed
EP-3438752-B1 POSITIVELY CHARGEABLE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEM CORP (JP) 2022-01-12 EP disclosed
CN-106892968-B Synthesis method of linaclotide 深圳翰宇药业股份有限公司 2021-11-05 CN disclosed
CN-108348402-B Polymerizable composition based on thermally cleavable compounds 义获嘉伟瓦登特公司 2021-02-02 CN disclosed
US-10667993-B2 Polymerizable compositions based on thermally cleavable compounds IVOCLAR VIVADENT AG (LI) 2020-06-02 US disclosed
EP-3156031-B9 POLYMERISABLE COMPOSITIONS BASED ON THERMALLY CLEAVABLE COMPOUNDS IVOCLAR VIVADENT AG (LI) 2020-03-18 EP disclosed
EP-3156031-B1 POLYMERISABLE COMPOSITIONS BASED ON THERMALLY CLEAVABLE COMPOUNDS IVOCLAR VIVADENT AG (LI) 2019-08-28 EP disclosed
EP-1762586-B1 Method for producing a crosslinked elastomer SEMPERIT AG HOLDING (AT) 2012-03-07 EP disclosed
EP-1219598-B1 PHENOLIC COMPOUNDS AND RECORDING MATERIALS CONTAINING THE SAME NIPPON SODA CO (JP) 2011-08-31 EP disclosed
US-20070105971-A1 METHOD FOR PRODUCING CROSS-LINKED ELASTOMER SEMPERIT AKTIENGESELLSCHAFT HOLDING (AT) 2007-05-10 US disclosed
EP-1762586-A2 Method for producing a crosslinked elastomer Semperit Aktiengesellschaft Holding (AT) 2007-03-14 EP disclosed
CN-1068324-C Novel pharmaceutical product LILLY CO ELI (US) 2001-07-11 CN disclosed
CN-1132205-A Novel pharmaceutical product LILLY CO ELI (US) 1996-10-02 CN disclosed
US-5491152-A Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-02-13 US disclosed
US-4988662-A MULTILAYER ELEMENT OF A COATED SUBSTRATE, A FILM WITH A COLOR-FORMING LACTONE, AN ACID AND A SENSITIZER DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-01-29 US disclosed
US-4988662-A MULTILAYER ELEMENT OF A COATED SUBSTRATE, A FILM WITH A COLOR-FORMING LACTONE, AN ACID AND A SENSITIZER DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-01-29 US disclosed
JP-H0229382-A THERMAL SENSITIVE RECORDING SHEET DAINIPPON INK & CHEM INC 1990-01-31 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10667993-B2 Polymerizable compositions based on thermally cleavable compounds CAD, TERB1, MLX ALDH1A1 1363/4885KMT2A 2159/4885HPGD 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.