Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.56 |
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20635358 | 0.80 | RAB9A (0.53) | RAB9ANPC1POLBCYP1A2CYP3A4 | |
| SCHEMBL13373999 | 0.76 | RAB9A (0.51) | RAB9ANPC1POLBALDH1A1MAPT | |
| SCHEMBL5840849 | 0.74 | CYP1A2 (0.50) | RAB9ANPC1POLBCYP1A2CYP3A4 | |
| SCHEMBL13373998 | 0.73 | MAPT (0.46) | RAB9ANPC1POLBCYP3A4ALDH1A1 | |
| SCHEMBL13373994 | 0.73 | ALDH1A1 (0.49) | RAB9ANPC1POLBALDH1A1MAPT | |
| SCHEMBL849744 | 0.72 | CYP1A2 (0.49) | RAB9ANPC1POLBCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL28901909 | 0.72 | CYP1A2 (0.49) | RAB9ANPC1POLBCYP1A2CYP3A4 | |
| SCHEMBL19339699 | 0.72 | CYP1A2 (0.49) | RAB9ANPC1POLBCYP1A2CYP3A4 | |
| SCHEMBL3177246 | 0.72 | CYP1A2 (0.45) | RAB9ANPC1POLBCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3464344 | 0.71 | CYP1A2 (0.47) | RAB9ANPC1POLBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |