Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12903035 | 0.85 | MAPT (0.55) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16620674 | 0.78 | MAPT (0.46) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13374001 | 0.77 | MAPT (0.43) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9290196 | 0.76 | MAPT (0.45) | MAPTGAANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27612556 | 0.75 | MAPT (0.44) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13532211 | 0.75 | ALDH1A1 (0.44) | MAPTGAANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13373999 | 0.73 | RAB9A (0.51) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13373995 | 0.73 | RAB9A (0.56) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3173764 | 0.73 | ALDH1A1 (0.42) | MAPTGAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5680273 | 0.72 | ALDH1A1 (0.53) | MAPTGAANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |