Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24663833 | 0.85 | POLB (0.54) | ACHEMGAT2 | |
| SCHEMBL13374365 | 0.85 | MEN1 (0.55) | BCHEACHEBACE1MGAT2 | |
| SCHEMBL13374346 | 0.85 | HRH1 (0.62) | BCHEACHEBACE1MGAT2 | |
| SCHEMBL22533356 | 0.85 | MGAT2 (0.52) | BCHEACHEBACE1MGAT2 | |
| SCHEMBL13602641 | 0.83 | TEAD1 (0.53) | MGAT2 | |
| SCHEMBL10236431 | 0.83 | ACHE (0.66) | BCHEACHEBACE1 | |
| SCHEMBL13374352 | 0.83 | ALDH1A1 (0.59) | ACHEMGAT2 | |
| SCHEMBL19075520 | 0.82 | SIGMAR1 (0.49) | MGAT2 | |
| SCHEMBL12437243 | 0.81 | ALDH1A1 (0.60) | ACHE | |
| SCHEMBL5411899 | 0.81 | HRH3 (0.73) | BCHEACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288381-B2 | N-9 substituted purine compounds, compositions and methods of use | GENENTECH, INC. (US) | 2012-10-16 | — | — | US | disclosed |