Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.35 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13375327 | 0.96 | ABL1 (0.37) | ABL1PDPK1KDM4ENPC1ALDH1A1 | |
| SCHEMBL13375182 | 0.89 | ABL1 (0.34) | ABL1PDPK1KDM4ENPC1ALDH1A1 | |
| SCHEMBL13375043 | 0.87 | ABL1 (0.37) | ABL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13375188 | 0.87 | ABL1 (0.36) | ABL1KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL13374025 | 0.86 | ALDH1A1 (0.39) | ABL1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13375199 | 0.86 | SYK (0.39) | ABL1 | |
| SCHEMBL13374024 | 0.82 | ALDH1A1 (0.42) | ABL1PDPK1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13375054 | 0.82 | ABL1 (0.33) | ABL1 | |
| SCHEMBL13375334 | 0.81 | ABL1 (0.34) | ABL1 | |
| SCHEMBL5951302 | 0.80 | ALDH1A1 (0.39) | ABL1KDM4EALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |