Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231420 | 0.85 | CASP2 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6233996 | 0.84 | CASP2 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22455889 | 0.81 | CNR1 (0.49) | CNR1FAAHCASP2DNM1NAAA | |
| SCHEMBL6236684 | 0.81 | CASP2 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL16302656 | 0.80 | FAAH (0.63) | CNR1FAAHCASP2DNM1NAAA | |
| SCHEMBL17860103 | 0.79 | TSHR (0.53) | CNR1FAAHCASP2DNM1NAAA | |
| SCHEMBL18415430 | 0.79 | HDAC3 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL27330437 | 0.78 | CNR1 (0.54) | CNR1FAAHCASP2DNM1NAAA | |
| SCHEMBL700736 | 0.78 | CASP2 (0.61) | CNR1FAAHCASP2DNM1NAAA | |
| SCHEMBL6239136 | 0.77 | MEN1 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288155-B2 | Biomolecular attachment sites on microelectronic arrays and methods thereof | GAMIDA FOR LIFE B.V. (NL) | 2012-10-16 | — | — | US | disclosed |