SCHEMBL6236684

SCHEMBL6236684

CCCC(=O)NCCSC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CASP2 P42575 1/20 0.52
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
GBA1 P04062 2/20 0.41
HPGD P15428 2/20 0.41
CTSD P07339 1/20 0.40
NAAA Q02083 1/20 0.40
FAAH O00519 3/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LPAR1 Q92633 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6231420 0.89 CASP2 (0.58) CASP2HDAC3HDAC1HDAC2HDAC8
SCHEMBL6233996 0.87 CASP2 (0.61) CASP2HDAC3HDAC1HDAC2HDAC8
SCHEMBL5500002 0.84 CASP2 (0.57) CASP2HDAC3HDAC1HDAC2HDAC8
SCHEMBL6238764 0.83 KMT2A (0.54) TSHRALDH1A1CYP2C19
SCHEMBL20118005 0.82 KMT2A (0.38) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL18714373 0.82 PHF8 (0.45) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL10954634 0.82 TSHR (0.52) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL14976750 0.81 CASP2 (0.57) CASP2HDAC3HDAC1HDAC2HDAC8
SCHEMBL13375652 0.81 HDAC3 (0.46) CASP2HDAC3HDAC1HDAC2HDAC8
SCHEMBL10490875 0.79 SLC6A5 (0.42) HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1531672-A2 ANTIMICROBIAL COMPOSITIONS Novus International, Inc. (US) 2005-05-25 EP disclosed
WO-2004019683-A2 ANTIMICROBIAL COMPOSITIONS NOVUS INTERNATIONAL, INC. (US) 2004-03-11 WO disclosed