SCHEMBL13375679

SCHEMBL13375679

Cc1ccc(C(=O)c2ccc(Oc3ccccc3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SRD5A2 P31213 7/20 0.72
▸ ALDH1A1 P00352 1/20 0.61
▸ LMNA P02545 1/20 0.61
▸ MAPK14 Q16539 1/20 0.60
▸ PARP10 Q53GL7 1/20 0.58
▸ MMP13 P45452 1/20 0.58
▸ HTT P42858 1/20 0.58
▸ SMN1; SMN2 Q16637 1/20 0.58
▸ ELANE P08246 1/20 0.56
▸ POLB P06746 1/20 0.56
▸ AKR1C3 P42330 1/20 0.55
▸ CES2 O00748 1/20 0.53
▸ CES1 P23141 1/20 0.53
▸ EPHX2 P34913 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6425454 0.96 SRD5A2 (0.67) SRD5A2ALDH1A1LMNAMAPK14MMP13
SCHEMBL14417496 0.95 SRD5A2 (0.66) SRD5A2ALDH1A1LMNAMAPK14PARP10
SCHEMBL822866 0.92 ALDH1A1 (0.73) SRD5A2ALDH1A1LMNAMAPK14PARP10
SCHEMBL16997316 0.92 ALDH1A1 (0.73) SRD5A2ALDH1A1LMNAMAPK14PARP10
SCHEMBL6384226 0.92 ALDH1A1 (0.73) SRD5A2ALDH1A1LMNAMAPK14PARP10
SCHEMBL24087885 0.92 ALDH1A1 (0.73) SRD5A2ALDH1A1LMNAMAPK14PARP10
SCHEMBL17049541 0.92 ALDH1A1 (0.73) SRD5A2ALDH1A1LMNAMAPK14PARP10
SCHEMBL10084164 0.92 ALDH1A1 (0.73) SRD5A2ALDH1A1LMNAMAPK14PARP10
SCHEMBL10001974 0.92 ALDH1A1 (0.73) SRD5A2ALDH1A1LMNAMAPK14PARP10
SCHEMBL822938 0.92 ALDH1A1 (0.73) SRD5A2ALDH1A1LMNAMAPK14PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227369-A1 HIGH TEMPERATURE COMPOSITES AND METHODS FOR PREPARING HIGH TEMPERATURE COMPOSITES ARKEMA FRANCE (FR) 2023-07-20 — — US disclosed
WO-2015177550-A1 AMINE AND NON-AMINE DERIVATISED POLYARYLETHERKETONE RANDOM AND BLOCK COPOLYMERS KETONEX LIMITED (GB) 2015-11-26 — — WO disclosed
WO-2015177549-A1 METHOD FOR MAKING PARTICULATE AMINE-FUNCTIONALIZED POLYARYLETHERKETONE POLYMERS AND COPOLYMERS THEREOF KETONEX LIMITED (GB) 2015-11-26 — — WO disclosed
WO-2015179587-A1 PARTICULATE AMINE-FUNCTIONALIZED POLYARYLETHERKETONE POLYMER AND COPOLYMERS THEREOF CYTEC INDUSTRIES INC. (US) 2015-11-26 — — WO disclosed
WO-2015177551-A1 PARTICULATE AROMATIC POLY(ETHER KETONE ETHER KETONE KETONES) KETONEX LIMITED (GB) 2015-11-26 — — WO disclosed
US-8288058-B2 Binder for fuel cell, composition for forming electrode, electrode, and fuel cell using the electrode MITSUI CHEMICALS, INC. (JP) 2012-10-16 — — US disclosed
US-20090149625-A1 AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP JSR CORPORATION (JP) 2009-06-11 — — US disclosed
US-20070292733-A1 Binder for Fuel Cell, Composition for Forming Electrode, Electrode, and Fuel Cell Using the Electrode MITSUI CHEMICALS, INC. (JP) 2007-12-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149625-A1 AROMATIC COMPOUND HAVING FLUORENE SKELETON AND POLYARYLENE HAVING SULFONIC ACID GROUP AFF2, FGFR1, FUS SRD5A2 1411/4885ALDH1A1 2176/4885LMNA 4093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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