Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | MMP13 | P45452 | 2/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.52 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.52 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.52 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10084164 | 1.00 | ALDH1A1 (0.73) | ALDH1A1LMNAMMP13SRD5A2HPGD | |
| SCHEMBL16997316 | 1.00 | ALDH1A1 (0.73) | ALDH1A1LMNAMMP13SRD5A2HPGD | |
| SCHEMBL6384226 | 1.00 | ALDH1A1 (0.73) | ALDH1A1LMNAMMP13SRD5A2HPGD | |
| SCHEMBL10001974 | 1.00 | ALDH1A1 (0.73) | ALDH1A1LMNAMMP13SRD5A2HPGD | |
| SCHEMBL822866 | 1.00 | ALDH1A1 (0.73) | ALDH1A1LMNAMMP13SRD5A2HPGD | |
| SCHEMBL24087885 | 1.00 | ALDH1A1 (0.73) | ALDH1A1LMNAMMP13SRD5A2HPGD | |
| SCHEMBL822938 | 1.00 | ALDH1A1 (0.73) | ALDH1A1LMNAMMP13SRD5A2HPGD | |
| SCHEMBL760051 | 0.94 | ALDH1A1 (0.64) | ALDH1A1LMNAMMP13SRD5A2HPGD | |
| SCHEMBL11974584 | 0.94 | ALDH1A1 (0.64) | ALDH1A1LMNAMMP13SRD5A2HPGD | |
| SCHEMBL14310920 | 0.92 | LMNA (0.61) | ALDH1A1LMNAMMP13SRD5A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9121442-B2 | Polymeric bearing articles for use in ultra-high pressure and velocity environments | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2015-09-01 | — | — | US | disclosed |