Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95390 | 0.94 | POLB (0.47) | KDM4EPOLBESR1ESR2CYP3A4 | |
| SCHEMBL18900422 | 0.88 | POLB (0.39) | KDM4EPOLBESR1ESR2CYP3A4 | |
| SCHEMBL173043 | 0.87 | ESR1 (0.50) | KDM4EPOLBESR1ESR2CYP3A4 | |
| SCHEMBL23617418 | 0.85 | KDM4E (0.40) | KDM4EPOLBESR1ESR2CYP3A4 | |
| SCHEMBL13917741 | 0.82 | ESR1 (0.45) | KDM4EPOLBESR1ESR2CYP3A4 | |
| SCHEMBL13473211 | 0.82 | ESR1 (0.45) | KDM4EPOLBESR1ESR2CYP3A4 | |
| SCHEMBL9677329 | 0.81 | MEN1 (0.49) | KDM4EPOLBESR1CYP3A4HSD17B10 | |
| SCHEMBL1129826 | 0.81 | KDM4E (0.51) | KDM4EPOLBESR1ESR2CYP3A4 | |
| SCHEMBL28427163 | 0.80 | POLB (0.47) | KDM4EPOLBCYP3A4HPGDTSHR | |
| SCHEMBL13452153 | 0.80 | SCN9A (0.37) | KDM4EPOLBESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2174970-A1 | POLYCARBONATE RESIN AND METHOD FOR PRODUCING THE SAME | Mitsubishi Chemical Corporation (JP) | 2010-04-14 | — | — | EP | disclosed |