SCHEMBL173043

SCHEMBL173043

CC(C)(c1ccc(O)cc1)c1ccc(Oc2ccc(C(C)(C)c3ccc(O)cc3)cc2C(=O)O)c(C(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.50
ESR2 Q92731 5/20 0.50
CYP3A4 P08684 3/20 0.50
HSD17B10 Q99714 3/20 0.50
HPGD P15428 2/20 0.50
TSHR P16473 2/20 0.50
AR P10275 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
HTR6 P50406 1/20 0.50
ESRRG P62508 1/20 0.50
SLC6A3 Q01959 1/20 0.50
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 2/20 0.40
POLB P06746 2/20 0.40
CFD P00746 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13473211 0.94 ESR1 (0.45) ESR1ESR2CYP3A4HSD17B10HPGD
SCHEMBL13917741 0.94 ESR1 (0.45) ESR1ESR2CYP3A4HSD17B10HPGD
SCHEMBL95390 0.93 POLB (0.47) ESR1ESR2CYP3A4HSD17B10HPGD
SCHEMBL24952432 0.91 ESR1 (0.42) ESR1ESR2CYP3A4HSD17B10HPGD
SCHEMBL13451844 0.89 ESR1 (0.41) ESR1ESR2CYP3A4HSD17B10HPGD
SCHEMBL95491 0.88 ESR1 (0.40) ESR1ESR2CYP3A4HSD17B10HPGD
SCHEMBL13376147 0.87 KDM4E (0.42) ESR1ESR2CYP3A4HSD17B10HPGD
SCHEMBL13979486 0.85 TSHR (0.47) ESR1ESR2CYP3A4HSD17B10HPGD
SCHEMBL23617418 0.85 KDM4E (0.40) ESR1ESR2CYP3A4HSD17B10HPGD
SCHEMBL18900422 0.83 POLB (0.39) ESR1ESR2CYP3A4HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3838979-B1 MELT POLYCARBONATE WITH IMPROVED OPTICAL PROPERTIES COVESTRO DEUTSCHLAND AG (DE) 2024-06-26 EP disclosed
US-20220195123-A1 SILOXANE-CONTAINING BLOCK COPOLYCARBONATES HAVING A SMALL DOMAIN SIZE COVESTRO DEUTSCHLAND AG (DE) 2022-06-23 US disclosed
EP-3950847-A1 LAMINATED SHEET CONTAINING SILOXANE BLOCK COPOLYCARBONATES AS MATRIX MATERIAL Covestro Intellectual Property GmbH & Co. KG (DE) 2022-02-09 EP disclosed
US-11161938-B2 Production of siloxane-containing block copolycarbonates by means of compatibilizers COVESTRO DEUTSCHLAND AG (DE) 2021-11-02 US disclosed
EP-3464471-B1 LAMINATED SHEET CONTAINING SPECIAL SILOXANE BLOCK COPOLYCARBONATES AS MATRIX MATERIAL COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2021-10-06 EP disclosed
US-11130321-B2 Multi-layer composite material containing special copolycarbonates as a matrix material COVESTRO DEUTSCHLAND AG (DE) 2021-09-28 US disclosed
EP-3838979-A1 MELT POLYCARBONATE WITH IMPROVED OPTICAL PROPERTIES Covestro Deutschland AG (DE) 2021-06-23 EP disclosed
US-20210171767-A1 THERMOPLASTIC COMPOSITIONS HAVING GOOD STABILITY COVESTRO DEUTSCHLAND AG (DE) 2021-06-10 US disclosed
US-10717871-B2 Flame-retardant, glass fiber-containing molding compounds containing siloxane-containing polycarbonate block co-condensate COVESTRO DEUTSCHLAND AG (DE) 2020-07-21 US disclosed
US-10407541-B2 Block co-condensates of polysiloxanes and dihydroxydiphenylcycloalkane-based n (CO)polycarbonates COVESTRO DEUTSCHLAND AG (DE) 2019-09-10 US disclosed
US-20110003945-A1 POLYCARBONATES COMPRISING CYCLIC OLIGOMERS AND HAVING AN IMPROVED FLOW BEHAVIOR BAYER MATERIALSCIENCE AG 2011-01-06 US disclosed
US-20100244303-A1 PRODUCTION METHOD OF AROMATIC POLYCARBONATE MITSUBISHI CHEMICAL CORPORATION (JP) 2010-09-30 US disclosed
EP-2143750-A1 Aromatic polycarbonate composition, process for producing the same, and hollow container therefrom Mitsubishi Chemical Corporation (JP) 2010-01-13 EP disclosed
WO-2009106246-A1 POLYCARBONATES COMPRISING CYCLIC OLIGOMERS AND HAVING AN IMPROVED FLOW BEHAVIOR BAYER MATERIALSCIENCE AG (DE) 2009-09-03 WO disclosed
US-7511114-B2 Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-31 US disclosed
US-7511114-B2 Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-31 US disclosed
US-7271235-B2 Branched aromatic polycarbonate and its production method MITSUBISHI CHEMICAL CORPORATION (JP) 2007-09-18 US disclosed
US-7271235-B2 Branched aromatic polycarbonate and its production method MITSUBISHI CHEMICAL CORPORATION (JP) 2007-09-18 US disclosed
US-20070129471-A1 Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container MITSUBISHI CHEMICAL CORPORATION (JP) 2007-06-07 US disclosed
US-20070129471-A1 Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container MITSUBISHI CHEMICAL CORPORATION (JP) 2007-06-07 US disclosed