SCHEMBL95390

SCHEMBL95390

CC(C)(c1ccc(O)cc1)c1ccc(Oc2ccc(C(C)(C)c3ccc(O)cc3)cc2C(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.47
KDM4E B2RXH2 3/20 0.47
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 2/20 0.46
AR P10275 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
HTR6 P50406 1/20 0.46
ESRRG P62508 1/20 0.46
SLC6A3 Q01959 1/20 0.46
ALDH1A1 P00352 1/20 0.45
SCN9A Q15858 1/20 0.43
XDH P47989 1/20 0.39
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
NPC1 O15118 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13376147 0.94 KDM4E (0.42) POLBKDM4EESR1ESR2CYP3A4
SCHEMBL173043 0.93 ESR1 (0.50) POLBKDM4EESR1ESR2CYP3A4
SCHEMBL23617418 0.91 KDM4E (0.40) POLBKDM4EESR1ESR2CYP3A4
SCHEMBL18900422 0.89 POLB (0.39) POLBKDM4EESR1ESR2CYP3A4
SCHEMBL13473211 0.87 ESR1 (0.45) POLBKDM4EESR1ESR2CYP3A4
SCHEMBL13917741 0.87 ESR1 (0.45) POLBKDM4EESR1ESR2CYP3A4
SCHEMBL1129826 0.87 KDM4E (0.51) POLBKDM4EESR1ESR2CYP3A4
SCHEMBL28427163 0.86 POLB (0.47) POLBKDM4ECYP3A4HPGDTSHR
SCHEMBL13452153 0.85 SCN9A (0.37) POLBKDM4EESR1ESR2CYP3A4
SCHEMBL24952432 0.84 ESR1 (0.42) POLBKDM4EESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3838979-B1 MELT POLYCARBONATE WITH IMPROVED OPTICAL PROPERTIES COVESTRO DEUTSCHLAND AG (DE) 2024-06-26 EP disclosed
EP-4309865-A1 METHOD FOR PRODUCING A COMPOSITE ARTICLE COMPRISING A SUPPORT COMPRISING A HYDROXYL COMPONENT Covestro Deutschland AG (DE) 2024-01-24 EP disclosed
EP-4309864-A1 METHOD FOR PRODUCING A COMPOSITE ARTICLE COMPRISING A SUPPORT COMPRISING POLYCARBONATE WITH SPECIFIC OH CONTENT Covestro Deutschland AG (DE) 2024-01-24 EP disclosed
US-20220195123-A1 SILOXANE-CONTAINING BLOCK COPOLYCARBONATES HAVING A SMALL DOMAIN SIZE COVESTRO DEUTSCHLAND AG (DE) 2022-06-23 US disclosed
US-11161938-B2 Production of siloxane-containing block copolycarbonates by means of compatibilizers COVESTRO DEUTSCHLAND AG (DE) 2021-11-02 US disclosed
US-11130321-B2 Multi-layer composite material containing special copolycarbonates as a matrix material COVESTRO DEUTSCHLAND AG (DE) 2021-09-28 US disclosed
EP-3838979-A1 MELT POLYCARBONATE WITH IMPROVED OPTICAL PROPERTIES Covestro Deutschland AG (DE) 2021-06-23 EP disclosed
US-20210171767-A1 THERMOPLASTIC COMPOSITIONS HAVING GOOD STABILITY COVESTRO DEUTSCHLAND AG (DE) 2021-06-10 US disclosed
US-10717871-B2 Flame-retardant, glass fiber-containing molding compounds containing siloxane-containing polycarbonate block co-condensate COVESTRO DEUTSCHLAND AG (DE) 2020-07-21 US disclosed
US-10407541-B2 Block co-condensates of polysiloxanes and dihydroxydiphenylcycloalkane-based n (CO)polycarbonates COVESTRO DEUTSCHLAND AG (DE) 2019-09-10 US disclosed
US-20110040066-A1 POLYCARBONATES HAVING REARRANGEMENT STRUCTURES, CYCLIC AND LINEAR OLIGOMERS AND ALSO FLOW BEHAVIOR BAYER MATERIALSCIENCE AG (DE) 2011-02-17 US disclosed
US-20110003945-A1 POLYCARBONATES COMPRISING CYCLIC OLIGOMERS AND HAVING AN IMPROVED FLOW BEHAVIOR BAYER MATERIALSCIENCE AG 2011-01-06 US disclosed
US-20110003945-A1 POLYCARBONATES COMPRISING CYCLIC OLIGOMERS AND HAVING AN IMPROVED FLOW BEHAVIOR BAYER MATERIALSCIENCE AG 2011-01-06 US disclosed
US-20100244303-A1 PRODUCTION METHOD OF AROMATIC POLYCARBONATE MITSUBISHI CHEMICAL CORPORATION (JP) 2010-09-30 US disclosed
WO-2009127366-A1 POLYCARBONATES HAVING REARRANGEMENT STRUCTURES, CYCLIC AND LINEAR OLIGOMERS AND ALSO IMPROVED FLOW BEHAVIOUR BAYER MATERIALSCIENCE AG (DE) 2009-10-22 WO disclosed
WO-2009106246-A1 POLYCARBONATES COMPRISING CYCLIC OLIGOMERS AND HAVING AN IMPROVED FLOW BEHAVIOR BAYER MATERIALSCIENCE AG (DE) 2009-09-03 WO disclosed
US-7511114-B2 Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-31 US disclosed
US-7511114-B2 Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-31 US disclosed
US-20070129471-A1 Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container MITSUBISHI CHEMICAL CORPORATION (JP) 2007-06-07 US disclosed
US-20070129471-A1 Colored aromatic polycarbonate resin composition, process for producing the same and colored hollow container MITSUBISHI CHEMICAL CORPORATION (JP) 2007-06-07 US disclosed