SCHEMBL1129826

SCHEMBL1129826

CC(C)(c1ccccc1)c1ccc(Oc2ccccc2)c(C(=O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.51
POLB P06746 4/20 0.51
TTR P02766 2/20 0.46
CTNNB1 P35222 1/20 0.44
SCN9A Q15858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 3/20 0.43
HPGD P15428 1/20 0.43
ESR1 P03372 1/20 0.42
CYP3A4 P08684 1/20 0.42
ESR2 Q92731 1/20 0.42
SCN8A Q9UQD0 1/20 0.42
SCN10A Q9Y5Y9 1/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KCNQ3 O43525 2/20 0.41
KCNQ2 O43526 2/20 0.41
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95390 0.87 POLB (0.47) KDM4EPOLBTTRSCN9AALDH1A1
SCHEMBL13917737 0.85 NPSR1 (0.49) KDM4EPOLBNPSR1L3MBTL1ALDH1A1
SCHEMBL28427163 0.84 POLB (0.47) KDM4EPOLBTTRCTNNB1SCN9A
SCHEMBL10689949 0.84 ALDH1A1 (0.43) KDM4EPOLBALDH1A1HPGDESR1
SCHEMBL10422051 0.83 NPC1 (0.46) KDM4EPOLBALDH1A1NPC1RAB9A
SCHEMBL6368079 0.82 ALDH1A1 (0.42) KDM4EPOLBALDH1A1HPGDESR1
SCHEMBL173043 0.82 ESR1 (0.50) KDM4EPOLBSCN9AL3MBTL1ALDH1A1
SCHEMBL13376147 0.81 KDM4E (0.42) KDM4EPOLBSCN9AALDH1A1HPGD
SCHEMBL4388725 0.81 ESR1 (0.46) KDM4ETTRCTNNB1NPSR1L3MBTL1
SCHEMBL8646508 0.80 HTT (0.51) KDM4EALDH1A1HPGDESR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283287-B2 Thermosensitive recording material RICOH COMPANY, LTD. (JP) 2012-10-09 US disclosed
EP-2036737-B1 Thermosensitive recording material RICOH CO LTD (JP) 2011-02-16 EP disclosed
US-20090075817-A1 THERMOSENSITIVE RECORDING MATERIAL RICOH COMPANY, LTD. (JP) 2009-03-19 US disclosed
EP-2036737-A1 Thermosensitive recording material Ricoh Company, Ltd. (JP) 2009-03-18 EP disclosed
US-4920091-A CONTAINING SALICYLIC ACID DERIVATIVE AS ELECTRON ACCEPTING COLOR DEVELOPER; STABLE IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1990-04-24 US disclosed
US-4918047-A CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
EP-0338808-A2 Alkyl salicylate resin for carbonless copy paper and imaging use SCHENECTADY INTERNATIONAL, INC. (US) 1989-10-25 EP disclosed
EP-0253666-A2 Heat-sensitive recording material containing dye-forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-01-20 EP disclosed