Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13067353 | 1.00 | OPRM1 (0.36) | OPRM1LMNAOPRD1OPRK1CYP1A2 | |
| SCHEMBL13151725 | 1.00 | OPRM1 (0.36) | OPRM1LMNAOPRD1OPRK1CYP1A2 | |
| SCHEMBL14161022 | 0.96 | HCRTR1 (0.37) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL18473427 | 0.87 | HCRTR1 (0.37) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL10111273 | 0.84 | HCRTR1 (0.38) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL13049584 | 0.81 | HCRTR1 (0.34) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL14161147 | 0.81 | HCRTR1 (0.40) | HCRTR1 | |
| SCHEMBL14161079 | 0.81 | OPRM1 (0.30) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13962904 | 0.78 | OPRM1 (0.37) | OPRM1OPRD1OPRK1CYP1A2PKM | |
| SCHEMBL13847996 | 0.77 | OPRM1 (0.36) | OPRM1OPRD1OPRK1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2180000-A1 | Improved process for the preparation of 6-alpha-hydroxy-n-alkylated opiates | Mallinckrodt Inc. (US) | 2010-04-28 | — | — | EP | disclosed |