Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22147326 | 0.93 | NR1I2 (0.37) | OPRM1OPRD1OPRK1NR1I2KCNH2 | |
| SCHEMBL13962904 | 0.90 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14292473 | 0.83 | OPRM1 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14161022 | 0.81 | HCRTR1 (0.37) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL18473427 | 0.81 | HCRTR1 (0.37) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL13848158 | 0.80 | HCRTR1 (0.32) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL12337178 | 0.79 | OPRM1 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL46013 | 0.79 | OPRD1 (0.32) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10111273 | 0.79 | HCRTR1 (0.38) | OPRM1OPRD1OPRK1HCRTR1 | |
| SCHEMBL13067353 | 0.77 | OPRM1 (0.36) | OPRM1OPRD1OPRK1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067275-A1 | N-OXIDES OF 4,5-EPOXY-MORPHINANIUM ANALOGS | PROGENICS PHARMACEUTICALS, INC (US) | 2009-05-28 | — | — | WO | disclosed |