Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18473427 | 0.88 | HCRTR1 (0.37) | HCRTR1OPRM1OPRD1OPRK1 | |
| SCHEMBL14161022 | 0.88 | HCRTR1 (0.37) | HCRTR1OPRM1OPRD1OPRK1 | |
| SCHEMBL13151725 | 0.84 | OPRM1 (0.36) | HCRTR1OPRM1OPRD1OPRK1 | |
| SCHEMBL13376201 | 0.84 | OPRM1 (0.36) | HCRTR1OPRM1OPRD1OPRK1 | |
| SCHEMBL13067353 | 0.84 | OPRM1 (0.36) | HCRTR1OPRM1OPRD1OPRK1 | |
| SCHEMBL13049584 | 0.82 | HCRTR1 (0.34) | HCRTR1OPRM1OPRD1OPRK1 | |
| SCHEMBL13962904 | 0.79 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13847996 | 0.79 | OPRM1 (0.36) | HCRTR1OPRM1OPRD1OPRK1 | |
| SCHEMBL46013 | 0.78 | OPRD1 (0.32) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14161147 | 0.75 | HCRTR1 (0.40) | HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046465-A1 | Processes for the Preparation of Morphinane and Morphinone Compounds | BROCK UNIVERSITY (CA) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046465-A1 | Processes for the Preparation of Morphinane and Morphinone Compounds | OPRM1, SRM, OPRK1 | HCRTR1 2709/4885OPRM1 1/4885OPRD1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.