Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376343 | 0.92 | ALDH1A1 (0.56) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL2774094 | 0.86 | SMN1; SMN2 (0.72) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8197165 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL49935 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL2696538 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11947426 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8011026 | 0.80 | PTPN1 (0.74) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10484140 | 0.80 | ALDH1A1 (0.96) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL561093 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7821030 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691647-B2 | Compositions for use as a signal generation component and methods of using same | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-7691647-B2 | Compositions for use as a signal generation component and methods of using same | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20090325316-A1 | Compositions for use as a Signal Generation Component and Methods of Using Same | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2009-12-31 | — | — | US | disclosed |
| US-20090325316-A1 | Compositions for use as a Signal Generation Component and Methods of Using Same | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2009-12-31 | — | — | US | disclosed |