SCHEMBL2774094

SCHEMBL2774094

CC(=O)CC(=O)c1ccc2ccccc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.72
KDM4E B2RXH2 3/20 0.72
HPGD P15428 2/20 0.72
PTPN1 P18031 1/20 0.62
ALDH1A1 P00352 3/20 0.58
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
CES2 O00748 1/20 0.57
CES1 P23141 1/20 0.57
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2C19 P33261 1/20 0.56
HIF1A Q16665 1/20 0.56
HDAC1 Q13547 5/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC3 O15379 2/20 0.51
HDAC2 Q92769 2/20 0.51
EGFR P00533 1/20 0.49
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29489791 0.88 PTPN1 (0.71) SMN1; SMN2KDM4EHPGDPTPN1ALDH1A1
SCHEMBL1974978 0.88 PTPN1 (0.71) SMN1; SMN2KDM4EHPGDPTPN1ALDH1A1
SCHEMBL13376342 0.86 ALDH1A1 (0.68) SMN1; SMN2KDM4EHPGDPTPN1ALDH1A1
SCHEMBL13376343 0.84 ALDH1A1 (0.56) SMN1; SMN2KDM4EHPGDPTPN1ALDH1A1
SCHEMBL28482006 0.84 CYP2A6 (0.58) SMN1; SMN2KDM4EHPGDPTPN1ALDH1A1
SCHEMBL8536512 0.84 SMN1; SMN2 (1.00) SMN1; SMN2KDM4EHPGDPTPN1ALDH1A1
SCHEMBL3373461 0.83 PTPN1 (0.65) SMN1; SMN2KDM4EHPGDPTPN1ALDH1A1
SCHEMBL1003111 0.83 KDM4E (0.65) SMN1; SMN2KDM4EHPGDPTPN1ALDH1A1
SCHEMBL29483367 0.83 KDM4E (0.65) SMN1; SMN2KDM4EHPGDPTPN1ALDH1A1
SCHEMBL12532349 0.82 NPC1 (0.68) SMN1; SMN2KDM4EHPGDPTPN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107177038-B Moisture-resistant MOF-5-like compound, preparation method and application 辽宁师范大学 2020-04-21 CN claimed
US-20240240077-A1 COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, AND LIGHTING INCLUDING SAME, AND COMPOUND TORAY INDUSTRIES, INC. (JP) 2024-07-18 US disclosed
CN-107177038-B Moisture-resistant MOF-5-like compound, preparation method and application 辽宁师范大学 2020-04-21 CN disclosed
US-8993246-B2 Luminescence assay method OY ARCTIC PARTNERS AB (FI) 2015-03-31 US disclosed
US-8933138-B2 Photo-latent titanium-chelate catalysts BASF SE (DE) 2015-01-13 US disclosed
EP-2175320-B1 ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION ADEKA CORP (JP) 2013-03-13 EP disclosed
US-8338081-B2 Alkali-developable photosensitive resin composition and β-diketone compound ADEKA CORPORATION (JP) 2012-12-25 US disclosed
US-20120259033-A1 PHOTO-LATENT TITANIUM-CHELATE CATALYSTS BASF SE (DE) 2012-10-11 US disclosed
US-20120220685-A1 PHOTO-LATENT TITANIUM CATALYSTS BASF SE (DE) 2012-08-30 US disclosed
EP-1496097-B1 Manufacturing method for luminous organic compound ORIENT CHEMICAL IND (JP) 2012-06-27 EP disclosed
US-4939138-A 2- and 3-aminomethyl-6-arylcarbonyl-2,3-dihydropyrrolo(1,2,3-DE)-1,4-benzoxazines STERLING DRUG INC. (US) 1990-07-03 US disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
US-4668799-A Anti-hepatitis and anti-cirrhotic 1,3-dithiol-2-ylidene derivatives, and pharmaceutical compositions therefor BANYU PHARMACEUTICAL CO., LTD. (JP) 1987-05-26 US disclosed
EP-0210284-A1 1,3-Dithiol-2-ylidene derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1987-02-04 EP disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4556621-A Electrophotographic recording material containing a metal-1,3-diketone complex BASF AKTIENGESELLSCHAFT (DE) 1985-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120259033-A1 PHOTO-LATENT TITANIUM-CHELATE CATALYSTS CCNT1, L3MBTL3, L3MBTL4 SMN1; SMN2 4864/4885KDM4E 530/4885HPGD 3668/4885
US-20240240077-A1 COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, AND LIGHTING INCLUDING SAME, AND COMPOUND CDYL, ZKSCAN2, CAD SMN1; SMN2 2052/4885KDM4E 478/4885HPGD 4419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.