SCHEMBL133803

SCHEMBL133803

NC(=O)NSCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.48
NOS1 P29475 2/20 0.48
NOS3 P29474 1/20 0.48
NOS2 P35228 1/20 0.48
CYP2C19 P33261 2/20 0.44
PLA2G10 O15496 1/20 0.41
PLA2G2A P14555 1/20 0.41
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
POLB P06746 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
KMT2A Q03164 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
AKR1B1 P15121 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10690050 0.98 IDO1 (0.50) IDO1NOS1NOS3NOS2CYP2C19
SCHEMBL27639758 0.89 LMNA (0.47) ALDH1A1HPGDLMNAMEN1KMT2A
SCHEMBL3063086 0.85 IDO1 (0.43) IDO1NOS1NOS3NOS2CYP2C19
SCHEMBL27660548 0.85 AOC3 (0.50)
SCHEMBL3078872 0.85 IDO1 (0.46) IDO1NOS1NOS3NOS2CYP2C19
SCHEMBL3080810 0.83 CYP2C19 (0.47) IDO1NOS1NOS3NOS2CYP2C19
SCHEMBL7844886 0.83 SMN1; SMN2 (0.47) IDO1NOS1NOS3NOS2CYP2C19
SCHEMBL3057987 0.83 IDO1 (0.44) IDO1NOS1NOS3NOS2CYP2C19
SCHEMBL13734757 0.82 NOS1 (0.48) NOS1CYP2C19ALDH1A1SMN1; SMN2LMNA
SCHEMBL27953297 0.82 NOS1 (0.42) IDO1NOS1ALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106084714-A A kind of agricultural mulching and preparation method thereof 吉林省农业科学院 2016-11-09 CN claimed
EP-1716197-B1 HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS BASF SE (DE) 2008-10-29 EP claimed
CN-100387320-C Chelation type hollow fiber affinity membrane chromatogram, its manufacturing method and use UNIV TIANJIN POLYTECHNIC (CN) 2008-05-14 CN claimed
CN-1768893-A Chelation type hollow fiber affinity membrane chromatogram, its manufacturing method and use UNIV TIANJIN POLYTECHNIC (CN) 2006-05-10 CN claimed
US-20250092020-A1 IDO/TDO Inhibitor GENERAL INCORPORATED ASSOCIATION PHARMA VALLEY PROJECT SUPPORTING ORGANIZATION (JP) 2025-03-20 US disclosed
US-12209079-B2 IDO/TDO inhibitor GENERAL INCORPORATED ASSOCIATION PHARMA VALLEY PROJECT SUPPORTING ORGANIZATION (JP) 2025-01-28 US disclosed
CN-119192087-A Chemical synthesis method of ergothioneine 镇江卡博医药科技有限公司 2024-12-27 CN disclosed
US-20220380305-A1 IDO/TDO Inhibitor CANBAS CO., LTD. 2022-12-01 US disclosed
US-20200239452-A1 IDO/TDO Inhibitor CANBAS CO., LTD. (JP) 2020-07-30 US disclosed
WO-2019078246-A1 IDO/TDO INHIBITOR 一般社団法人ファルマバレープロジェクト支援機構 2019-04-25 WO disclosed
CN-108743446-A A kind of ultrafiltration membrane preparation method of cocoon sericin protein and its application 中国科学院新疆理化技术研究所 2018-11-06 CN disclosed
CN-107582588-A A kind of purposes of the white phoenix dish extractive of general flavone and preparation method thereof with treating alcoholic fatty liver 漳州片仔癀药业股份有限公司 2018-01-16 CN disclosed
US-6933304-B2 Heteroarylalkanoic acids as integrin receptor antagonists PHARMACIA CORPORATION (US) 2005-08-23 US disclosed
CN-1589153-A Prevention or treatment of urinary disorders TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2005-03-02 CN disclosed
US-20040092497-A1 Heteroarylakanoic acids as intergrin receptor antagonists PHARMACIA CORPORATION 2004-05-13 US disclosed
CN-1117754-C Indolomorphinane derivatives and remedies/preventives for cerebral disorders TORAY INDUSTRIES (JP) 2003-08-13 CN disclosed
EP-1289983-A2 HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS Pharmacia Corporation (US) 2003-03-12 EP disclosed
US-20020133023-A1 Heteroarylalkanoic acids as integrin receptor antagonists PHARMACIA CORPORATION 2002-09-19 US disclosed
WO-2001096334-A2 HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS PHARMACIA CORPORATION (US) 2001-12-20 WO disclosed
CN-1220668-A INDOLOMORPHINANE DERIVATIVES AND REMEDIES/PREVENTIVES FOR CEREBRAL DISORDERS TORAY INDUSTRIES (JP) 1999-06-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12209079-B2 IDO/TDO inhibitor IDO1, IDO2, TDO2 IDO1 1/4885NOS1 233/4885NOS3 494/4885
US-20020133023-A1 Heteroarylalkanoic acids as integrin receptor antagonists ITGA5, ITGA2B, ITGAV IDO1 3607/4885NOS1 4741/4885NOS3 4391/4885
US-20040092497-A1 Heteroarylakanoic acids as intergrin receptor antagonists ITGA5, ITGB7, ITGA2B IDO1 2548/4885NOS1 4111/4885NOS3 3632/4885
US-20200239452-A1 IDO/TDO Inhibitor IDO1, IDO2, TDO2 IDO1 1/4885NOS1 233/4885NOS3 494/4885
US-20250092020-A1 IDO/TDO Inhibitor IDO1, IDO2, TDO2 IDO1 1/4885NOS1 233/4885NOS3 494/4885
US-20220380305-A1 IDO/TDO Inhibitor IDO1, IDO2, TDO2 IDO1 1/4885NOS1 174/4885NOS3 438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.