Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12418891 | 0.91 | ALDH1A1 (0.32) | PDK2ROCK2 | |
| SCHEMBL12508298 | 0.90 | KMT2A (0.31) | PDK2 | |
| SCHEMBL14627858 | 0.68 | — | — | |
| SCHEMBL14597208 | 0.68 | — | — | |
| SCHEMBL18365336 | 0.67 | — | — | |
| SCHEMBL18882644 | 0.66 | — | — | |
| SCHEMBL12418894 | 0.65 | FKBP1A (0.36) | PDK2ROCK2 | |
| SCHEMBL14470094 | 0.63 | POLB (0.33) | ROCK2 | |
| SCHEMBL14452143 | 0.63 | POLB (0.33) | ROCK2 | |
| SCHEMBL18526248 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081203-A1 | FLUORESCENT ISOTOPE TAGS AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2010-04-01 | — | — | US | disclosed |
| US-20090017546-A1 | FLUORESCENT ISOTOPE TAGS AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017546-A1 | FLUORESCENT ISOTOPE TAGS AND THEIR METHOD OF USE | SRMS, TMEM14C, HM13 | PDK2 4039/4885ROCK2 2748/4885 |
| US-20100081203-A1 | FLUORESCENT ISOTOPE TAGS AND THEIR METHOD OF USE | SRMS, TMEM14C, HM13 | PDK2 4039/4885ROCK2 2748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.