SCHEMBL133815

SCHEMBL133815

NC=CCC(=O)[C@H](N)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.53
SLCO1B1 Q9Y6L6 1/20 0.53
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PDE4A P27815 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1696945 0.80 USP2 (0.55) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL246985 0.80 USP2 (0.55) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL27661966 0.73 USP2 (0.33) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL5436780 0.72 USP2 (0.65) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL8803522 0.72 USP2 (0.64) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL9064623 0.71 USP2 (0.53) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL9064886 0.71 USP2 (0.53) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL9065107 0.71 USP2 (0.53) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL14938558 0.70 USP2 (0.57) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL7263034 0.70 USP2 (0.57) USP2SLCO1B1LMNAL3MBTL1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106456546-A Liposomal compositions for mucosal delivery 葛兰素史密丝克莱恩生物有限公司 2017-02-22 CN claimed
CN-106893724-B Oligonucleotide with antigen synergism and tumor treatment effect 苏州派动生物技术有限公司 2023-05-02 CN disclosed
US-11081235-B2 Extracellular matrix metalloproteinase inducer (EMMPRIN) peptides and binding antibodies MOR-RESEARCH APPLICATIONS LTD. (IL) 2021-08-03 US disclosed
US-20190309031-A1 EXTRACELLULAR MATRIX METALLOPROTEINASE INDUCER (EMMPRIN) PEPTIDES AND BINDING ANTIBODIES MOR - RESEARCH APPLICATIONS LTD. (IL) 2019-10-10 US disclosed
US-10426828-B2 Compositions of multimeric-multiepitope influenza polypeptides and their production BIONDVAX PHARMACEUTICALS LTD. (IL) 2019-10-01 US disclosed
CN-110229813-A Oligonucleotides with vaccine adjuvant effect and oncotherapy effect 苏州派动生物技术有限公司 2019-09-13 CN disclosed
EP-3492095-A1 EXTRACELLULAR MATRIX METALLOPROTEINASE INDUCER (EMMPRIN) PEPTIDES AND BINDING ANTIBODIES Technion Research & Development Foundation Limited (IL) 2019-06-05 EP disclosed
US-20180318415-A1 NOVEL ADJUVANT FORMULATIONS GLAXOSMITHKLINE BIOLOGICALS, SA (BE) 2018-11-08 US disclosed
EP-3386540-A1 NOVEL ADJUVANT FORMULATIONS GlaxoSmithKline Biologicals S.A. (BE) 2018-10-17 EP disclosed
EP-2833900-B1 EXTRACELLULAR MATRIX METALLOPROTEINASE INDUCER (EMMPRIN) PEPTIDES AND BINDING ANTIBODIES TECHNION RES & DEV FOUNDATION (IL) 2018-09-19 EP disclosed
EP-0983286-B1 AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORP (US) 2004-07-28 EP disclosed
US-20040029279-A1 Packaging of positive-strand rna virus replicon particles WYETH HOLDINGS CORPORATION 2004-02-12 US disclosed
US-20030198645-A1 Vaccines; stimulant of lymphocytes against hepatatis; induce immunology response APOVIA INC. 2003-10-23 US disclosed
EP-1326990-A2 PACKAGING OF POSITIVE-STRAND RNA VIRUS REPLICON PARTICLES Wyeth Holdings Corporation (US) 2003-07-16 EP disclosed
US-6355257-B1 Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors CORIXA CORPORATION 2002-03-12 US disclosed
WO-2002018585-A2 PACKAGING OF POSITIVE-STRAND RNA VIRUS REPLICON PARTICLES WYETH HOLDINGS CORPORATION (US) 2002-03-07 WO disclosed
US-6113918-A IMMUNOLOGY RIBI IMMUNOCHEM RESEARCH, INC. (US) 2000-09-05 US disclosed
CN-1265112-A Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors KRIKSA LTD (US) 2000-08-30 CN disclosed
EP-0983286-A1 AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 2000-03-08 EP disclosed
WO-1998050399-A1 AMINOALKYL GLUCOSAMINE PHOSPHATE COMPOUNDS AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS CORIXA CORPORATION (US) 1998-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11081235-B2 Extracellular matrix metalloproteinase inducer (EMMPRIN) peptides and binding antibodies BSG, MMP7, CD14 USP2 4540/4885SLCO1B1 2954/4885LMNA 1793/4885
US-20180318415-A1 NOVEL ADJUVANT FORMULATIONS LGALS3BP, LGALS2, LGALS4 USP2 2366/4885SLCO1B1 1863/4885LMNA 4801/4885
US-20190309031-A1 EXTRACELLULAR MATRIX METALLOPROTEINASE INDUCER (EMMPRIN) PEPTIDES AND BINDING ANTIBODIES BSG, MMP7, CD14 USP2 4540/4885SLCO1B1 2954/4885LMNA 1793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.