Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13383562 | 0.86 | AURKA (0.41) | NPC1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL13383587 | 0.79 | AURKA (0.37) | ALDH1A1MAPK1AURKA | |
| SCHEMBL13383578 | 0.78 | AURKA (0.55) | NPC1RAB9AKMT2ACDK2MEN1 | |
| SCHEMBL13530368 | 0.78 | ALDH1A1 (0.50) | NPC1RAB9AKMT2ACCNE1CDK2 | |
| SCHEMBL15424939 | 0.78 | AURKA (0.35) | AURKAJAK2AURKB | |
| SCHEMBL1270948 | 0.77 | SMN1; SMN2 (0.50) | NPC1RAB9AKMT2ACDK2CDK5 | |
| SCHEMBL3183680 | 0.77 | KMT2A (0.46) | KMT2AALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL15890236 | 0.75 | NPC1 (0.50) | NPC1RAB9ANPSR1KMT2AF2 | |
| SCHEMBL25160143 | 0.74 | KMT2A (0.48) | NPC1RAB9ANPSR1KMT2ACCNE1 | |
| SCHEMBL25278641 | 0.73 | RAB9A (0.50) | NPC1RAB9ANPSR1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140296065-A1 | USE OF 5-FLUOROCYTOSINE AS A FUNGICIDE | DOW AGROSCIENCES LLC (IN) | 2014-10-02 | — | — | US | disclosed |
| US-20140296065-A1 | USE OF 5-FLUOROCYTOSINE AS A FUNGICIDE | DOW AGROSCIENCES LLC (IN) | 2014-10-02 | — | — | US | disclosed |
| EP-2317851-B1 | USE OF 5-FLUOROCYTOSINE AS A FUNGICIDE | DOW AGROSCIENCES LLC (US) | 2014-01-15 | — | — | EP | disclosed |
| EP-2647287-A1 | Use of 5-fluorocytosine and its derivatives as fungicides | Dow AgroSciences LLC (US) | 2013-10-09 | — | — | EP | disclosed |
| WO-2010047866-A2 | USE OF 5-FLUOROCYTOSINE AS A FUNGICIDE | DOW AGROSCIENCES LLC (US) | 2010-04-29 | — | — | WO | disclosed |
| US-20100029482-A1 | USE OF 5-FLUOROCYTOSINE AS A FUNGICIDE | DOW AGROSCIENCES LLC | 2010-02-04 | — | — | US | disclosed |
| US-20100029482-A1 | USE OF 5-FLUOROCYTOSINE AS A FUNGICIDE | DOW AGROSCIENCES LLC | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029482-A1 | USE OF 5-FLUOROCYTOSINE AS A FUNGICIDE | PFAS, DCTD, MTAP | NPC1 3756/4885RAB9A 954/4885NPSR1 4467/4885 |
| US-20140296065-A1 | USE OF 5-FLUOROCYTOSINE AS A FUNGICIDE | PFAS, DCTD, MTAP | NPC1 3756/4885RAB9A 954/4885NPSR1 4467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.