Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16106614 | 1.00 | CA2 (0.36) | CA2HSD17B10ALDH1A1 | |
| SCHEMBL19771000 | 1.00 | CA2 (0.36) | CA2HSD17B10ALDH1A1 | |
| SCHEMBL20181308 | 0.97 | — | — | |
| SCHEMBL800846 | 0.97 | — | — | |
| SCHEMBL20181307 | 0.97 | — | — | |
| SCHEMBL31360426 | 0.93 | CA2 (0.33) | CA2 | |
| SCHEMBL18905555 | 0.93 | CA2 (0.33) | CA2 | |
| SCHEMBL12269417 | 0.89 | ALDH1A1 (0.37) | HSD17B10ALDH1A1 | |
| SCHEMBL12695269 | 0.89 | ALDH1A1 (0.37) | HSD17B10ALDH1A1 | |
| Water SCHEMBL28694307 | 0.87 | ALDH1A1 (0.35) | HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981535-B1 | UREA DERIVATIVES USEFUL AS KINASE INHIBITORS | TOPIVERT PHARMA LTD (GB) | 2020-12-16 | — | — | EP | disclosed |
| US-10435361-B2 | Kinase inhibitors | TOPIVERT PHARMA LIMITED (GB) | 2019-10-08 | — | — | US | disclosed |
| US-20180044288-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2018-02-15 | — | — | US | disclosed |
| US-9790174-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-10-17 | — | — | US | disclosed |
| US-20160376232-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2016-12-29 | — | — | US | disclosed |
| US-9481648-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2016-11-01 | — | — | US | disclosed |
| EP-2981535-A1 | UREA DERIVATIVES USEFUL AS KINASE INHIBITORS | Respivert Limited (GB) | 2016-02-10 | — | — | EP | disclosed |
| WO-2014162126-A1 | UREA DERIVATIVES USEFUL AS KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2014-10-09 | — | — | WO | disclosed |
| US-20140296208-A1 | KINASE INHIBITORS | TOPIVERT PHARMA LIMITED (GB) | 2014-10-02 | — | — | US | disclosed |
| US-8071814-B2 | Process for preparing polyetheramines | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-12-06 | — | — | US | disclosed |
| US-7696385-B2 | Polyetheramine production method | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20100069671-A1 | Process For Preparing Polyetheramines | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-03-18 | — | — | US | disclosed |
| US-20090177013-A1 | Polyetheramine Production Method | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044288-A1 | KINASE INHIBITORS | SYK, LYN, BTK | CA2 2538/4885HSD17B10 4720/4885ALDH1A1 4408/4885 |
| US-20090177013-A1 | Polyetheramine Production Method | PNMT, HRH3, HRH4 | CA2 690/4885HSD17B10 1117/4885ALDH1A1 2133/4885 |
| US-20160376232-A1 | KINASE INHIBITORS | LYN, SYK, LCK | CA2 2848/4885HSD17B10 3142/4885ALDH1A1 3120/4885 |
| US-10435361-B2 | Kinase inhibitors | SYK, LYN, BTK | CA2 2538/4885HSD17B10 4720/4885ALDH1A1 4408/4885 |
| US-20100069671-A1 | Process For Preparing Polyetheramines | OXER1, OXGR1, NR1H3 | CA2 731/4885HSD17B10 123/4885ALDH1A1 2544/4885 |
| US-20140296208-A1 | KINASE INHIBITORS | SYK, LYN, BTK | CA2 2538/4885HSD17B10 4720/4885ALDH1A1 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.