Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295793 | 0.92 | TP53 (0.62) | CNR2TP53HDAC1HDAC6HDAC3 | |
| SCHEMBL16125596 | 0.88 | TP53 (0.54) | CNR2TP53HDAC1HDAC6HDAC3 | |
| SCHEMBL14851886 | 0.88 | TP53 (0.54) | CNR2TP53HDAC1HDAC6HDAC3 | |
| SCHEMBL657674 | 0.86 | CNR2 (0.58) | CNR2TP53HDAC1HDAC6HDAC3 | |
| SCHEMBL657957 | 0.84 | SMN1; SMN2 (0.66) | CNR2TP53HDAC1HDAC6HDAC3 | |
| SCHEMBL16125593 | 0.83 | HDAC1 (0.57) | CNR2TP53HDAC1HDAC6HDAC3 | |
| SCHEMBL16125595 | 0.83 | HDAC1 (0.81) | HDAC1HDAC6HDAC3HDAC4HDAC2 | |
| SCHEMBL1928093 | 0.83 | PKM (0.54) | TP53MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL16125603 | 0.82 | RORC (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL16125626 | 0.81 | HDAC1 (0.55) | CNR2TP53HDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | disclosed |