Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001626 | 0.90 | ADRA2C (0.65) | TP53ADRA2CALDH1A1ADRB2HPGD | |
| SCHEMBL9809224 | 0.87 | HPGD (0.66) | PKMTP53ALDH1A1HPGDMEN1 | |
| SCHEMBL1926647 | 0.86 | ADRA2C (0.53) | TP53ADRA2CALDH1A1ADRB2HPGD | |
| SCHEMBL16125620 | 0.83 | HDAC6 (0.63) | ADRA2CALDH1A1ADRB2HPGD | |
| SCHEMBL1926257 | 0.83 | TRPM8 (0.64) | ADRA2CALDH1A1ADRB2HPGDMEN1 | |
| SCHEMBL16125622 | 0.83 | ALDH1A1 (0.53) | TP53ADRA2CALDH1A1ADRB2HPGD | |
| SCHEMBL13386233 | 0.83 | CNR2 (0.63) | TP53ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6569544 | 0.82 | PKM (0.56) | PKMADRA2CALDH1A1HPGDMEN1 | |
| SCHEMBL12876177 | 0.82 | ADRA2C (0.52) | PKMTP53ADRA2CALDH1A1ADRB2 | |
| SCHEMBL12031549 | 0.81 | NPC1 (0.67) | PKMALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8257611-B2 | Optical film and retardation sheet, and liquid crystal compound | FUJIFILM CORPORATION (JP) | 2012-09-04 | — | — | US | disclosed |
| US-7956216-B2 | Benzoyl urea derivatives mimicing BH3-only proteins, able to interact with a Bcl-2 protein | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2011-06-07 | — | — | US | disclosed |
| US-20100045901-A1 | OPTICAL FILM AND RETARDATION SHEET, AND LIQUID CRYSTAL COMPOUND | FUJIFILM CORPORATION (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20080153802-A1 | Alpha-helical mimetics | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153802-A1 | Alpha-helical mimetics | BID, BAX, BAD | PKM 3582/4885TP53 64/4885ADRA2C 4297/4885 |
| US-20100045901-A1 | OPTICAL FILM AND RETARDATION SHEET, AND LIQUID CRYSTAL COMPOUND | C1R, CCNA1, C5 | PKM 4199/4885TP53 2713/4885ADRA2C 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.