SCHEMBL13387367

SCHEMBL13387367

COc1cc(C)c(C#N)cc1C

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
S1PR1 P21453 1/20 0.46
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
AR P10275 8/20 0.44
SRC P12931 2/20 0.41
IMPDH2 P12268 1/20 0.41
IMPDH1 P20839 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
CASP3 P42574 1/20 0.38
CASP7 P55210 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10541124 0.89 AR (0.47) ALDH1A1S1PR1KDM4EUSP2AR
SCHEMBL1039728 0.87 AR (0.54) ALDH1A1S1PR1KDM4EUSP2AR
SCHEMBL27376906 0.82 SRC (0.45) ALDH1A1KDM4EUSP2ARSRC
SCHEMBL15646608 0.82 KDM4E (0.42) ALDH1A1S1PR1KDM4EUSP2AR
Acetonitrile SCHEMBL6315753 0.81 TAAR1 (0.47) ALDH1A1KDM4EUSP2ARTAAR1
SCHEMBL119203 0.81 TSHR (0.50) ALDH1A1S1PR1KDM4EUSP2AR
SCHEMBL12650894 0.79 AR (0.40) ALDH1A1S1PR1KDM4EUSP2AR
SCHEMBL14036532 0.79 POLB (0.54) ALDH1A1KDM4EUSP2ARIMPDH2
SCHEMBL2954181 0.78 TAAR1 (0.56) ALDH1A1KDM4ETAAR1
SCHEMBL14993875 0.78 ALDH1A1 (0.50) ALDH1A1KDM4EUSP2ARIMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120270092-A1 LITHIUM ION SECONDARY BATTERY AND BATTERY PACK SYSTEM HITACHI, LTD. 2012-10-25 US disclosed
US-7514563-B2 Producing cyano-substituted pyridine, pyrrole, furan, thiophene or benzene boranes by reacting a cyanoarene with a BH or a HBBH compound, especially 4,4,5,5-tetramethyl-1,3,2-dioxborolane or its dimer, in the presence of an organo-phosphorus or -nitrogen iridium complex; drug intermediates BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2009-04-07 US disclosed