Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11889187 | 0.82 | LMNA (0.46) | MAPTCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL3274613 | 0.81 | MAPT (0.62) | MAPTCYP1A2CYP2C9CYP2C19NCEH1 | |
| SCHEMBL27740253 | 0.79 | MAPT (0.60) | MAPTCYP1A2CYP2C9CYP2C19NCEH1 | |
| SCHEMBL11807725 | 0.79 | NCEH1 (0.54) | MAPTCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL2327449 | 0.79 | MAPT (0.64) | MAPTLMNANCEH1CYP2A6SMN1; SMN2 | |
| Lonaprofen SCHEMBL29670159 | 0.78 | NCEH1 (0.56) | MAPTCYP1A2CYP2C9CYP2C19LMNA | |
| Lonaprofen SCHEMBL2109183 | 0.78 | NCEH1 (0.56) | MAPTCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL5610039 | 0.78 | MAPT (0.63) | MAPTCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL13323849 | 0.78 | MAPT (0.58) | MAPTCYP1A2CYP2C9CYP2C19NCEH1 | |
| SCHEMBL28419514 | 0.78 | MAPT (0.58) | MAPTCYP1A2CYP2C9CYP2C19NCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093747-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | CELTAXSYS, INC. | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093747-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | PMAIP1, CDC42, DCX | MAPT 4842/4885CYP1A2 4827/4885CYP2C9 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.