Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
| ▸ | NQO1 | P15559 | 1/20 | 0.51 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.51 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.51 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960504 | 0.90 | MAP2K1 (0.65) | ALDH1A1HPGDSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL959681 | 0.85 | MAP2K1 (0.73) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL959705 | 0.84 | HSD17B3 (0.65) | ALDH1A1HPGDSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL15917454 | 0.80 | ALDH1A1 (0.74) | ALDH1A1HPGDSMN1; SMN2LMNAKDM4E | |
| SCHEMBL961450 | 0.79 | NQO1 (0.47) | ALDH1A1HPGDSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL14317937 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HPGDSMN1; SMN2LMNAKDM4E | |
| SCHEMBL14048846 | 0.77 | KDM4E (0.45) | ALDH1A1HPGDSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL964530 | 0.77 | KDM4E (0.45) | ALDH1A1HPGDSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL961165 | 0.77 | TP53 (0.49) | ALDH1A1HPGDSMN1; SMN2LMNAKDM4E | |
| SCHEMBL31980592 | 0.77 | MAP2K1 (0.70) | ALDH1A1HPGDSMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172198-A1 | p27 PROTEIN INDUCER | Chugai Seiyaku Kabushiki Kaisha (JP) | 2010-04-07 | — | — | EP | disclosed |