Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.74 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.74 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.74 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.74 |
| ▸ | STS | P08842 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.69 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.69 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.67 |
| ▸ | ACLY | P53396 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24627780 | 0.89 | MAPT (0.72) | ALDH1A1ALDH1A2ALDH1B1ALDH1A3STS | |
| SCHEMBL29527739 | 0.87 | ALDH1A1 (0.88) | ALDH1A1ALDH1A2ALDH1B1ALDH1A3STS | |
| SCHEMBL970190 | 0.86 | MAP2K1 (0.70) | ALDH1A1ALDH1A2ALDH1B1ALDH1A3STS | |
| SCHEMBL972176 | 0.84 | ALDH1A1 (0.78) | ALDH1A1ALDH1A2ALDH1B1ALDH1A3STS | |
| SCHEMBL26434307 | 0.84 | ALDH1A1 (0.84) | ALDH1A1ALDH1A2ALDH1B1ALDH1A3STS | |
| SCHEMBL14317937 | 0.83 | ALDH1A1 (0.60) | ALDH1A1ALDH1A2ALDH1B1ALDH1A3STS | |
| SCHEMBL2247578 | 0.83 | MAP2K1 (0.81) | ALDH1A1ALDH1A2ALDH1B1ALDH1A3STS | |
| SCHEMBL29527472 | 0.82 | ALDH1A1 (0.68) | ALDH1A1ALDH1A2ALDH1B1ALDH1A3STS | |
| SCHEMBL971942 | 0.82 | KDM4E (1.00) | ALDH1A1ALDH1A2ALDH1B1ALDH1A3STS | |
| SCHEMBL12204222 | 0.81 | KDM4E (0.70) | ALDH1A1ALDH1A2ALDH1B1ALDH1A3STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334256-B2 | Agents and methods for treating ischemic and other diseases | NONO INC. (CA) | 2016-05-10 | — | — | US | disclosed |
| US-20140221423-A1 | Agents And Methods For Treating Ischemic And Other Diseases | NONO INC. (CA) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221423-A1 | Agents And Methods For Treating Ischemic And Other Diseases | TRPM7, TRPM8, TRPM5 | ALDH1A1 1722/4885ALDH1A2 95/4885ALDH1B1 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.