Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | EEF2K | O00418 | 10/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3166845 | 0.85 | ALDH1A1 (0.79) | ALDH1A1HPGDLMNANPSR1TDP1 | |
| SCHEMBL429207 | 0.84 | ALDH1A1 (1.00) | ALDH1A1HPGDLMNANPSR1TDP1 | |
| SCHEMBL13392917 | 0.84 | ALDH1A1 (0.81) | ALDH1A1HPGDLMNANPSR1TDP1 | |
| SCHEMBL429444 | 0.83 | ALDH1A1 (0.70) | ALDH1A1HPGDLMNANPSR1TDP1 | |
| SCHEMBL13941637 | 0.82 | ALDH1A1 (0.96) | ALDH1A1HPGDLMNANPSR1TDP1 | |
| SCHEMBL13393359 | 0.82 | ALDH1A1 (0.78) | ALDH1A1HPGDLMNANPSR1TDP1 | |
| SCHEMBL13392945 | 0.81 | ALDH1A1 (0.73) | ALDH1A1HPGDLMNANPSR1TDP1 | |
| SCHEMBL2853029 | 0.76 | ALDH1A1 (0.73) | ALDH1A1HPGDLMNANPSR1TDP1 | |
| SCHEMBL426621 | 0.76 | MAPT (1.00) | ALDH1A1HPGDLMNANPSR1TDP1 | |
| SCHEMBL22957838 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HPGDLMNANPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099672-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2010-04-22 | — | — | US | disclosed |
| US-20100099672-A1 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2010-04-22 | — | — | US | disclosed |
| US-7645881-B2 | Such as tert-Butyl 3-amino-5-ethyl-4,6-dimethylthieno[2,3-B]pyridine-2-carboxylate which inhibits replication | PTC THERAPEUTICS, INC. (US) | 2010-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099672-A1 | METHODS FOR TREATING HEPATITIS C | OAT, HAVCR2, HCCS | ALDH1A1 539/4885HPGD 1023/4885LMNA 3095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.