Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 11/20 | 0.79 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.79 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | PI4KA | P42356 | 2/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16603993 | 0.90 | AHCY (0.85) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| (S)-Dhpa SCHEMBL936286 | 0.88 | AHCY (1.00) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| (S)-Dhpa SCHEMBL936287 | 0.88 | AHCY (1.00) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| (S)-Dhpa SCHEMBL28605202 | 0.88 | AHCY (1.00) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL11487766 | 0.87 | ADORA2A (0.71) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL13394190 | 0.87 | ADORA2A (0.72) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL28068456 | 0.85 | AHCY (0.78) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL8839648 | 0.84 | AHCY (0.68) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL14963614 | 0.84 | ADORA2A (0.76) | AHCYADORA2AADORA1ALDH1A1PI4KA | |
| SCHEMBL13394189 | 0.84 | ADORA2A (0.76) | AHCYADORA2AADORA1ALDH1A1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8884011-B2 | Nucleotide analogues as precursor molecules for antivirals | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2014-11-11 | — | — | US | disclosed |
| US-8884011-B2 | Nucleotide analogues as precursor molecules for antivirals | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2014-11-11 | — | — | US | disclosed |
| US-20100099869-A1 | NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2010-04-22 | — | — | US | disclosed |
| US-20100099869-A1 | NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099869-A1 | NOVEL NUCLEOTIDE ANALOGUES AS PRECUSOR MOLECULES FOR ANTIVIRALS | NUDT1, P2RY1, HPRT1 | AHCY 203/4885ADORA2A 79/4885ADORA1 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.