(S)-Dhpa

(S)-Dhpa

SCHEMBL936286

Nc1ncnc2c1ncn2C[C@H](O)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AHCY P23526 10/20 1.00
ADORA2A P29274 7/20 1.00
ADORA1 P30542 5/20 0.71
ALDH1A1 P00352 1/20 0.66
PI4KA P42356 2/20 0.58
PI4K2B Q8TCG2 2/20 0.58
PI4K2A Q9BTU6 2/20 0.58
PI4KB Q9UBF8 2/20 0.58
ADORA2B P29275 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(S)-Dhpa SCHEMBL936287 1.00 AHCY (1.00) AHCYADORA2AADORA1ALDH1A1PI4KA
(S)-Dhpa SCHEMBL28605202 1.00 AHCY (1.00) AHCYADORA2AADORA1ALDH1A1PI4KA
SCHEMBL16603993 0.92 AHCY (0.85) AHCYADORA2AADORA1ALDH1A1PI4KA
SCHEMBL13394191 0.88 AHCY (0.79) AHCYADORA2AADORA1ALDH1A1PI4KA
SCHEMBL28068456 0.88 AHCY (0.78) AHCYADORA2AADORA1ALDH1A1PI4KA
SCHEMBL2556536 0.87 AHCY (0.76) AHCYADORA2AADORA1ALDH1A1PI4KA
SCHEMBL14963614 0.87 ADORA2A (0.76) AHCYADORA2AADORA1ALDH1A1PI4KA
SCHEMBL2556539 0.87 AHCY (0.76) AHCYADORA2AADORA1ALDH1A1PI4KA
SCHEMBL13394189 0.87 ADORA2A (0.76) AHCYADORA2AADORA1ALDH1A1PI4KA
SCHEMBL11474105 0.87 AHCY (0.76) AHCYADORA2AADORA1ALDH1A1PI4KA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230110614-A1 HEPARIN AND N-ACETYLCYSTEINE FOR THE TREATMENT OF A RESPIRATORY VIRUS ATOSSA THERAPEUTICS, INC. 2023-04-13 US claimed
EP-4125936-A1 HEPARIN AND N-ACETYLCYSTEINE FOR THE TREATMENT OF A RESPIRATORY VIRUS Atossa Therapeutics, Inc. (US) 2023-02-08 EP claimed
WO-2021194890-A1 HEPARIN AND N-ACETYLCYSTEINE FOR THE TREATMENT OF A RESPIRATORY VIRUS ATOSSA THERAPEUTICS, INC. (US) 2021-09-30 WO claimed
US-20210299143-A1 USE OF ANTAGONISTS TO THE NUCLEAR STEROID RECEPTOR TO INHIBIT CORONAVIRUSES Spectral Analytics, Inc. (US) 2021-09-30 US claimed
US-20150057243-A1 Compositions and Methods for the Inhibition of Methyltransferases NORTHERN UNIVERSITY (US) 2015-02-26 US claimed
US-20130023491-A1 BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-01-24 US claimed
EP-2513298-A2 BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE President and Fellows of Harvard College (US) 2012-10-24 EP claimed
WO-2011075665-A2 BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2011-06-23 WO claimed
EP-0539493-B1 TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES BODOR NICHOLAS S (US) 1997-03-26 EP claimed
EP-0577725-A4 TARGETED DRUG DELIVERY VIA MIXED PHOSPHATE DERIVATIVES UNIV FLORIDA (US) 1996-04-17 EP claimed
WO-1992017185-A1 TARGETED DRUG DELIVERY VIA MIXED PHOSPHATE DERIVATIVES UNIVERSITY OF FLORIDA (US) 1992-10-15 WO claimed
US-5087618-A Antiviral, anticancer, antitumor agents UNIVERSITY OF FLORIDA (US) 1992-02-11 US claimed
WO-1992000988-A1 TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES BODOR NICHOLAS S (US) 1992-01-23 WO claimed
EP-0262696-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1988-04-06 EP claimed
EP-0222425-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-05-20 EP claimed
EP-0221588-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-05-13 EP claimed
EP-0218300-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-04-15 EP claimed
EP-0110955-A1 BRAIN-SPECIFIC DRUG DELIVERY. UNIV FLORIDA (US) 1984-06-20 EP claimed
WO-1983003968-A1 BRAIN-SPECIFIC DRUG DELIVERY UNIVERSITY OF FLORIDA (US) 1983-11-24 WO claimed
US-4230708-A SYNERGISTIC STICHTING REGA V.Z.W. (BE) 1980-10-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130023491-A1 BETA-CELL REPLICATION PROMOTING COMPOUNDS AND METHODS OF THEIR USE ADK, AHCY, IAPP AHCY 2/4885ADORA2A 169/4885ADORA1 330/4885
US-20150057243-A1 Compositions and Methods for the Inhibition of Methyltransferases RNMT, EMG1, NSUN2 AHCY 33/4885ADORA2A 3039/4885ADORA1 3989/4885
US-20210299143-A1 USE OF ANTAGONISTS TO THE NUCLEAR STEROID RECEPTOR TO INHIBIT CORONAVIRUSES NCOA1, NCOA2, NCOA3 AHCY 3060/4885ADORA2A 2496/4885ADORA1 2642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.