SCHEMBL13394563

SCHEMBL13394563

CC(C)(C)OC(=O)N[C@@H]1C[C@@H](n2cnnc2)CC[C@@H]1NC(=O)OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CPB1 P15086 2/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ PDE4B Q07343 1/20 0.42
▸ TACR1 P25103 2/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ SYK P43405 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ CCR2 P41597 1/20 0.40
▸ KDM1A O60341 1/20 0.40
▸ MAOB P27338 1/20 0.40
▸ CTSL P07711 2/20 0.40
▸ CTSB P07858 1/20 0.39
▸ CTSK P43235 1/20 0.39
▸ RORC P51449 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3305234 0.90 CPB1 (0.50) CPB1KMT2AL3MBTL1PDE4BTACR1
SCHEMBL3305241 0.90 CPB1 (0.50) CPB1KMT2AL3MBTL1PDE4BTACR1
SCHEMBL3302438 0.87 CPB1 (0.46) CPB1KMT2AL3MBTL1PDE4BTACR1
SCHEMBL1504068 0.81 ALDH1A1 (0.58) CPB1KMT2AL3MBTL1PDE4BTACR1
SCHEMBL12101156 0.81 CPB1 (0.56) CPB1KMT2AL3MBTL1PDE4BTACR1
SCHEMBL3302555 0.81 CPB1 (0.56) CPB1KMT2AL3MBTL1PDE4BTACR1
SCHEMBL3302548 0.81 CPB1 (0.56) CPB1KMT2AL3MBTL1PDE4BTACR1
SCHEMBL3302546 0.81 CPB1 (0.56) CPB1KMT2AL3MBTL1PDE4BTACR1
SCHEMBL10476662 0.81 ALDH1A1 (0.58) CPB1KMT2AL3MBTL1PDE4BTACR1
SCHEMBL4033681 0.81 CPB1 (0.54) CPB1KMT2AL3MBTL1PDE4BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100099660-A1 METHOD FOR TREATING THROMBOSIS OR EMBOLISM AND RELATED DISEASES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2010-04-22 — — US disclosed
US-20100099660-A1 METHOD FOR TREATING THROMBOSIS OR EMBOLISM AND RELATED DISEASES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2010-04-22 — — US disclosed
US-20090281074-A1 DRUG COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING THROMBOSIS OR EMBOLISM DAIICHI PHARMACEUTICAL CO., LTD (JP) 2009-11-12 — — US disclosed
US-20090281074-A1 DRUG COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING THROMBOSIS OR EMBOLISM DAIICHI PHARMACEUTICAL CO., LTD (JP) 2009-11-12 — — US disclosed
US-7576135-B2 Diamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2009-08-18 — — US disclosed
US-7576135-B2 Diamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2009-08-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099660-A1 METHOD FOR TREATING THROMBOSIS OR EMBOLISM AND RELATED DISEASES F2, PLAT, MPL CPB1 507/4885KMT2A 2546/4885L3MBTL1 1698/4885
US-20090281074-A1 DRUG COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING THROMBOSIS OR EMBOLISM C1R, C9, F2 CPB1 2714/4885KMT2A 3693/4885L3MBTL1 1605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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