Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3563686 | 0.97 | KMT2A (0.56) | CPB1EPHX1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL30441712 | 0.91 | KMT2A (0.53) | CPB1EPHX1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3898660 | 0.90 | ALDH1A1 (0.65) | CPB1KMT2AL3MBTL1ALDH1A1GAA | |
| SCHEMBL3888143 | 0.90 | ALDH1A1 (0.61) | CPB1EPHX1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3888150 | 0.90 | ALDH1A1 (0.61) | CPB1EPHX1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3898666 | 0.90 | ALDH1A1 (0.65) | CPB1KMT2AL3MBTL1ALDH1A1GAA | |
| SCHEMBL6612597 | 0.89 | EPHX1 (0.63) | CPB1EPHX1KMT2AALDH1A1GAA | |
| SCHEMBL10137650 | 0.88 | CPB1 (0.56) | CPB1KMT2AL3MBTL1ALDH1A1PDE4B | |
| SCHEMBL12873056 | 0.88 | CPB1 (0.56) | CPB1KMT2AL3MBTL1ALDH1A1PDE4B | |
| SCHEMBL4358020 | 0.87 | ALDH1A1 (0.50) | CPB1EPHX1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611109-A4 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-06-24 | — | — | EP | disclosed |
| EP-1611109-A1 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004087680-A1 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004087669-A1 | NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO. LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |