SCHEMBL133958

SCHEMBL133958

CCOC(=O)[C@@H](N)Cc1c[nH]c2ccccc12

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 2/20 0.72
MAPT P10636 5/20 0.68
KDM4E B2RXH2 3/20 0.68
LMNA P02545 2/20 0.68
MEN1 O00255 1/20 0.68
MPO P05164 1/20 0.68
TSHR P16473 1/20 0.68
BLM P54132 1/20 0.68
PMP22 Q01453 1/20 0.68
KMT2A Q03164 1/20 0.68
HIF1A Q16665 1/20 0.68
SCN9A Q15858 1/20 0.65
PKM P14618 1/20 0.63
HTR2A P28223 2/20 0.59
ADRB1 P08588 1/20 0.58
HTR1A P08908 1/20 0.58
ADRA2A P08913 1/20 0.58
SLC6A2 P23975 1/20 0.58
HTR1D P28221 1/20 0.58
HTR1B P28222 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL839065 1.00 TACR1 (0.72) TACR1MAPTKDM4ELMNAMEN1
SCHEMBL29632750 1.00 TACR1 (0.72) TACR1MAPTKDM4ELMNAMEN1
SCHEMBL840121 1.00 TACR1 (0.72) TACR1MAPTKDM4ELMNAMEN1
Hydrochloric Acid SCHEMBL18185353 0.99 TACR1 (0.71) TACR1MAPTKDM4ELMNAMEN1
Hydrochloric Acid SCHEMBL133957 0.99 TACR1 (0.71) TACR1MAPTKDM4ELMNAMEN1
Hydrochloric Acid SCHEMBL29400769 0.99 TACR1 (0.71) TACR1MAPTKDM4ELMNAMEN1
Hydrochloric Acid SCHEMBL133956 0.99 TACR1 (0.71) TACR1MAPTKDM4ELMNAMEN1
Hydrochloric Acid SCHEMBL5485888 0.99 TACR1 (0.71) TACR1MAPTKDM4ELMNAMEN1
Hydrochloric Acid SCHEMBL5485884 0.99 TACR1 (0.71) TACR1MAPTKDM4ELMNAMEN1
Acetic Acid SCHEMBL28587206 0.95 TACR1 (0.67) TACR1MAPTKDM4ELMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673426-A1 FUNCTIONALIZED BIODEGRADABLE SURFACTANTS AND METHODS USE Locus Solutions IPCO, LLC (US) 2026-01-07 EP claimed
CN-119470406-A Phthalic dicarboxaldehyde disinfectant concentration detection test paper and preparation method thereof 山东新华莎罗雅生物技术有限公司 2025-02-18 CN claimed
US-20240301322-A1 FUNCTIONALIZED BIODEGRADABLE SURFACTANTS AND METHODS USE LOCUS SOLUTIONS IPCO LLC (US) 2024-09-12 US claimed
WO-2024182125-A1 FUNCTIONALIZED BIODEGRADABLE SURFACTANTS AND METHODS USE LOCUS SOLUTIONS IPCO, LLC (US) 2024-09-06 WO claimed
CN-118290421-A Chiral probe compound based on flavin skeleton and preparation and application thereof 西北师范大学 2024-07-05 CN claimed
US-20240181394-A1 SYSTEM AND METHOD FOR RECOVERING ORGANIC ACID PRODUCTS FROM A MULTICOMPONENT FEED SOLUTION THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2024-06-06 US claimed
CN-117362291-A Tetrahydro-beta-carboline phenol derivative, preparation method and application thereof, and whitening cream 广州番禺职业技术学院 2024-01-09 CN claimed
CN-115093410-A Preparation method of beta-carboline compound 南京工业大学 2022-09-23 CN claimed
CN-111574710-B Dendritic tryptophan compound, preparation method thereof and application thereof as antibacterial agent 威海晨源分子新材料有限公司 2022-07-01 CN claimed
CN-111518275-B Dendritic tryptophan compound, preparation method thereof and application thereof as virus invasion inhibitor 威海晨源分子新材料有限公司 2022-07-01 CN claimed
CN-1789399-A Soft compound and use thereof PROCTER & GAMBLE (US) 2006-06-21 CN claimed
EP-1113795-B1 TRYPTOPHANYL ESTERS AND THEIR N-ACYL DERIVATIVES FOR THE PREVENTION AND TREATMENT OF DISEASES CAUSED OR EXACERBATED BY OXIDATION PROCESSES MAX PLANCK GESELLSCHAFT (DE) 2005-07-13 EP claimed
US-20040176436-A1 Tryptophanyl-esters and their N-acyl derivatives for preventing and treating diseases caused or aggravated by oxidation processes BEHL CHRISTIAN (DE) 2004-09-09 US claimed
US-6306203-B1 FOR USE IN INK JET PRINTING, INCLUDING PIEZOELECTRIC INK JET PRINTING AND ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-10-23 US claimed
CN-1309690-A Amine reactive compounds comprising one or more active ingredients PROCTER & GAMBLE (US) 2001-08-22 CN claimed
US-20010014695-A1 Tryptophanyl-esters and their n-acyl derivatives for preventing and treating diseases caused or aggravated by oxidation processes MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2001-08-16 US claimed
EP-1113795-A2 TRYPTOPHANYL ESTER AND THEIR N-ACYL DERIVATIVES FOR THE PREVENTION AND TREATMENT OF DISEASES CAUSED OR EXACERBATED BY OXIDATION PROCESSES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2001-07-11 EP claimed
US-6191168-B1 BACTERICIDES Rubenstein, Edward 2001-02-20 US claimed
WO-2000015206-A2 TRYPTOPHANYL ESTER AND THEIR N-ACYL DERIVATIVES FOR THE PREVENTION AND TREATMENT OF DISEASES CAUSED OR EXACERBATED BY OXIDATION PROCESSES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2000-03-23 WO claimed
EP-0085283-A1 Pyroglutamyl-tryptophan derivatives, process for their preparation and their therapeutic applications Società Italo-Britannica L. Manetti - H. Roberts & C. (IT) 1983-08-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176436-A1 Tryptophanyl-esters and their N-acyl derivatives for preventing and treating diseases caused or aggravated by oxidation processes AADAT, KYNU, AADAC TACR1 4551/4885MAPT 521/4885KDM4E 2274/4885
US-20010014695-A1 Tryptophanyl-esters and their n-acyl derivatives for preventing and treating diseases caused or aggravated by oxidation processes AADAT, KYNU, AANAT TACR1 4354/4885MAPT 409/4885KDM4E 2637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.