Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296522 | 0.82 | MDM2 (0.44) | NAPRTMAPTRAB9AHPGDLMNA | |
| SCHEMBL296132 | 0.81 | NPC1 (0.50) | SMN1; SMN2RAB9ANPC1LMNACDK5 | |
| SCHEMBL29396801 | 0.81 | NPC1 (0.50) | SMN1; SMN2RAB9ANPC1LMNACDK5 | |
| SCHEMBL5514973 | 0.78 | NAPRT (0.46) | NAPRTHSD17B10MAPTSMN1; SMN2RAB9A | |
| SCHEMBL1646972 | 0.78 | NAPRT (0.46) | NAPRTHSD17B10MAPTSMN1; SMN2RAB9A | |
| SCHEMBL27472867 | 0.77 | GAA (0.45) | HSD17B10MAPTRAB9ATP53HPGD | |
| SCHEMBL23629736 | 0.77 | NAPRT (0.45) | NAPRTHSD17B10MAPTSMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL8791650 | 0.77 | NAPRT (0.45) | NAPRTHSD17B10MAPTSMN1; SMN2RAB9A | |
| SCHEMBL27554730 | 0.77 | PDK1 (0.47) | NAPRTHSD17B10MAPTSMN1; SMN2RAB9A | |
| SCHEMBL3697578 | 0.76 | PDK1 (0.41) | NAPRTHSD17B10MAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8062899-B1 | Identification and quantitative determination of major chemical contaminants associated with L-Tryptophan | NHK Laboratories, Inc. (US) | 2011-11-22 | — | — | US | disclosed |