SCHEMBL5514973

SCHEMBL5514973

CC(Nc1ccccc1)(C(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MAPT P10636 4/20 0.46
TSHR P16473 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TP53 P04637 1/20 0.44
EPHX1 P07099 1/20 0.44
EPHX2 P34913 1/20 0.44
CDK9 P50750 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
PDK1 Q15118 2/20 0.44
PDK2 Q15119 2/20 0.44
PDK3 Q15120 2/20 0.44
PDK4 Q16654 2/20 0.44
CYP3A4 P08684 1/20 0.43
ALOX5 P09917 1/20 0.43
HSP90AA1 P07900 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
RAB9A P51151 2/20 0.42
GAA P10253 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1646972 0.82 NAPRT (0.46) NAPRTHSD17B10MAPTTSHRSMN1; SMN2
SCHEMBL8795980 0.81 MAPT (0.49) MAPTSMN1; SMN2CYP3A4RAB9AGAA
SCHEMBL28531503 0.81 MAPT (0.59) NAPRTHSD17B10MAPTTSHRSMN1; SMN2
SCHEMBL27554730 0.80 PDK1 (0.47) NAPRTHSD17B10MAPTTSHRSMN1; SMN2
Hydrochloric Acid SCHEMBL8791650 0.80 NAPRT (0.45) NAPRTHSD17B10MAPTTSHRSMN1; SMN2
SCHEMBL23629736 0.80 NAPRT (0.45) NAPRTHSD17B10MAPTTSHRSMN1; SMN2
SCHEMBL1339748 0.78 NAPRT (0.43) NAPRTHSD17B10MAPTTSHRSMN1; SMN2
SCHEMBL15204405 0.78 PDK1 (0.50) NAPRTHSD17B10MAPTTSHRSMN1; SMN2
SCHEMBL27512207 0.78 CLCN2 (0.43) GAAHPGDKCNK9
SCHEMBL11350456 0.77 NAPRT (0.52) NAPRTHSD17B10MAPTTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed