Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070768 | 0.91 | THRA (0.76) | THRATHRB | |
| SCHEMBL13855347 | 0.90 | THRA (0.74) | THRATHRB | |
| SCHEMBL3157285 | 0.90 | THRA (0.81) | THRATHRB | |
| SCHEMBL287727 | 0.89 | THRA (1.00) | THRATHRB | |
| SCHEMBL3152027 | 0.88 | THRA (0.81) | THRATHRB | |
| SCHEMBL3161952 | 0.87 | THRA (0.84) | THRATHRB | |
| SCHEMBL18774708 | 0.85 | THRA (0.67) | THRATHRB | |
| SCHEMBL4215570 | 0.84 | THRA (0.79) | THRATHRB | |
| SCHEMBL4203769 | 0.84 | THRA (0.65) | THRATHRB | |
| SCHEMBL3160909 | 0.82 | THRA (1.00) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081634-A1 | Novel Phosphorus-Containing Thyromimetics | METABASIS THERAPEUTICS, INC. (US) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081634-A1 | Novel Phosphorus-Containing Thyromimetics | PYGL, THRA, THOP1 | THRA 2/4885THRB 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.