Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 2/20 | 0.76 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.51 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.51 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4096497 | 0.87 | ALDH1A1 (0.61) | AKR1C2AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL13401489 | 0.84 | ALDH1A1 (0.72) | AKR1C2AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL1308635 | 0.84 | AKR1C2 (0.65) | AKR1C2AKR1C1MEN1KMT2AKDM4E | |
| SCHEMBL6353682 | 0.83 | AKR1C2 (0.71) | AKR1C2AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL5950280 | 0.83 | MEN1 (0.62) | AKR1C2AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL6359133 | 0.81 | AKR1C2 (0.68) | AKR1C2AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL1455196 | 0.80 | KMT2A (0.73) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL17166275 | 0.79 | AKR1C2 (0.73) | AKR1C2AKR1C1ALDH1A1MEN1KMT2A | |
| SCHEMBL3619864 | 0.79 | MAPT (0.61) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6352508 | 0.79 | AKR1C2 (0.70) | AKR1C2AKR1C1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815860-B1 | Phosphate transport inhibitors | GENZYME CORP (US) | 2010-04-21 | — | — | EP | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021509-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC20A1 | AKR1C2 257/4885AKR1C1 239/4885ALDH1A1 2163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.