Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 5/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14272920 | 0.91 | CCR5 (0.47) | CCR5TACR1PDE4APDE4BPDE4C | |
| SCHEMBL3322159 | 0.89 | SLC6A3 (0.53) | CCR5TACR1SLC6A2SLC6A4 | |
| SCHEMBL13484599 | 0.89 | CCR5 (0.52) | CCR5TACR1SLC6A2SLC6A4PDE4A | |
| SCHEMBL7462568 | 0.87 | CCR5 (0.56) | CCR5TACR1SLC6A2SLC6A4PDE4A | |
| SCHEMBL3466111 | 0.87 | CCR5 (0.48) | CCR5TACR1SLC6A2SLC6A4PDE4A | |
| SCHEMBL3466112 | 0.87 | CCR5 (0.48) | CCR5TACR1SLC6A2SLC6A4PDE4A | |
| SCHEMBL7462578 | 0.87 | CCR5 (0.56) | CCR5TACR1SLC6A2SLC6A4PDE4A | |
| SCHEMBL652130 | 0.86 | MEN1 (0.53) | CCR5TACR1MEN1KMT2AOPRD1 | |
| SCHEMBL14415543 | 0.85 | CCR5 (0.55) | CCR5TACR1PDE4APDE4BPDE4C | |
| SCHEMBL13543969 | 0.85 | CCR5 (0.53) | CCR5TACR1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691893-B2 | Chemical compounds | GLAXO GROUP LIMITED (GB) | 2010-04-06 | — | — | US | disclosed |
| US-20080114049-A1 | CHEMICAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114049-A1 | CHEMICAL COMPOUNDS | SLC6A2, HTR3C, SLC6A3 | CCR5 1053/4885TACR1 90/4885SLC6A2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.