SCHEMBL9618990

SCHEMBL9618990

O=C1C(=Cc2ccccc2[N+](=O)[O-])SC(=S)N1c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.56
KMT2A Q03164 6/20 0.56
MAPT P10636 4/20 0.55
ALDH1A1 P00352 4/20 0.55
TDP1 Q9NUW8 3/20 0.55
POLB P06746 2/20 0.54
NOD2 Q9HC29 1/20 0.54
MAPK1 P28482 2/20 0.54
KDM4E B2RXH2 1/20 0.54
THRB P10828 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
DUSP22 Q9NRW4 5/20 0.54
AMY1A P0DUB6 1/20 0.52
BCL2 P10415 1/20 0.52
TDP2 O95551 1/20 0.51
CASP7 P55210 1/20 0.51
CASP9 P55211 1/20 0.51
CASP6 P55212 1/20 0.51
CASP8 Q14790 1/20 0.51
CFTR P13569 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618989 1.00 MEN1 (0.56) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL13401425 0.80 DUSP22 (0.57) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL9618992 0.80 DUSP22 (0.54) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL9120921 0.80 DUSP22 (0.64) MEN1KMT2AALDH1A1TDP1DUSP22
SCHEMBL12123516 0.80 DUSP22 (0.77) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL9917038 0.80 DUSP22 (0.77) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL10035996 0.80 DUSP22 (0.77) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL3897914 0.79 HTRA2 (0.71) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL3897920 0.79 HTRA2 (0.71) MEN1KMT2AMAPTALDH1A1TDP1
SCHEMBL6279044 0.79 HTRA2 (0.71) MEN1KMT2AMAPTALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3970459-A Process for developing a direct reversal silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed
EP-0300382-B1 PHOTOGRAPHIC EMULSION AND ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-01-08 EP disclosed
US-5049483-A Containing a 2-mercapto (benz) imidazole or a (benzo) triazole compound as antistatic agent KONICA CORPORATION (JP) 1991-09-17 US disclosed
EP-0401846-A2 A direct positive silver halide photographic light-sensitive material and a processing method therefor KONICA CORPORATION (JP) 1990-12-12 EP disclosed
US-4808516-A HIGH SPEED, CONTRAST EASTMAN KODAK COMPANY (US) 1989-02-28 US disclosed
EP-0300382-A1 Photographic emulsion and element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-01-25 EP disclosed
US-RE29930-E HIGH SPEED EASTMAN KODAK COMPANY (US) 1979-03-13 US disclosed
US-4097285-A CYANINE DYE MITSUBISHI PAPER MILLS, LTD. (JA) 1978-06-27 US disclosed
US-RE29575-E Cubic regular grain photographic reversal emulsions EASTMAN KODAK COMPANY (US) 1978-03-14 US disclosed
US-4011081-A DIRECT-POSITIVE DOUBLE EXPOSURE PROCESS UTILIZING A PRIMITIVE, UNFOGGED SILVER HALIDE EMULSION CONTAINING AN ELECTRON ACCEPTOR EASTMAN KODAK COMPANY (US) 1977-03-08 US disclosed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US disclosed
US-3970459-A Process for developing a direct reversal silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US disclosed