Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 1/20 | 0.66 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.64 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723000 | 0.84 | HSD11B1 (0.62) | SELPHSD11B1PTPN1XDHMEN1 | |
| SCHEMBL29993031 | 0.84 | SELP (0.45) | SELPHSD11B1XDHACHE | |
| SCHEMBL527086 | 0.84 | SELP (0.45) | SELPHSD11B1XDHACHE | |
| SCHEMBL29440878 | 0.82 | HSD11B1 (0.59) | SELPHSD11B1PTPN1XDHMEN1 | |
| SCHEMBL29993378 | 0.82 | SELP (0.44) | SELPHSD11B1PTPN1XDHPTPN2 | |
| SCHEMBL24834667 | 0.79 | HSD11B1 (1.00) | SELPHSD11B1F10PTPN1PTPN2 | |
| SCHEMBL14704498 | 0.79 | HSD11B1 (1.00) | SELPHSD11B1F10PTPN1PTPN2 | |
| SCHEMBL14690730 | 0.79 | HSD11B1 (1.00) | SELPHSD11B1F10PTPN1PTPN2 | |
| SCHEMBL16491619 | 0.79 | HSD11B1 (1.00) | SELPHSD11B1F10PTPN1PTPN2 | |
| SCHEMBL19522314 | 0.79 | HSD11B1 (1.00) | SELPHSD11B1F10PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | GEUNS JOANNES | 2010-04-22 | — | — | US | disclosed |
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | GEUNS JOANNES | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | SORD, CASP3, TXNRD2 | SELP 125/4885HSD11B1 187/4885F10 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.