SCHEMBL13401724

SCHEMBL13401724

CC12CCC[C@@](C)(C(=O)O)[C@H]1CCC13C[C@](C)(CC[C@H]12)[C@](C)(O)C3

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
F10 P00742 6/20 0.60
PTPN1 P18031 4/20 0.58
PTPN2 P17706 1/20 0.58
CDC25B P30305 1/20 0.58
HSD11B1 P28845 2/20 0.57
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.47
KMT2A Q03164 1/20 0.47
MMP2 P08253 1/20 0.43
SELP P16109 1/20 0.43
ATM Q13315 1/20 0.42
HIF1A Q16665 1/20 0.41
EPAS1 Q99814 1/20 0.41
CYP2C9 P11712 1/20 0.41
HSP90AA1 P07900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21754703 0.86 F10 (0.60) F10PTPN1PTPN2CDC25BHSD11B1
SCHEMBL24834650 0.86 F10 (0.60) F10PTPN1PTPN2CDC25BHSD11B1
SCHEMBL24834731 0.86 F10 (0.60) F10PTPN1PTPN2CDC25BHSD11B1
SCHEMBL13078280 0.86 F10 (0.56) F10PTPN1PTPN2CDC25BHSD11B1
SCHEMBL13078295 0.82 F10 (0.55) F10PTPN1PTPN2CDC25BHSD11B1
SCHEMBL22922183 0.81 F10 (0.60) F10PTPN1PTPN2CDC25BHSD11B1
SCHEMBL21397914 0.81 F10 (0.60) F10PTPN1PTPN2CDC25BHSD11B1
SCHEMBL24834728 0.80 F10 (0.61) F10PTPN1PTPN2CDC25BHSD11B1
SCHEMBL24834669 0.78 HSD11B1 (0.63) F10PTPN1PTPN2CDC25BHSD11B1
SCHEMBL22922186 0.78 F10 (0.66) F10PTPN1PTPN2CDC25BHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100099640-A1 TISSUE DEGENERATION PROTECTION GEUNS JOANNES 2010-04-22 US disclosed
US-20100099640-A1 TISSUE DEGENERATION PROTECTION GEUNS JOANNES 2010-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099640-A1 TISSUE DEGENERATION PROTECTION SORD, CASP3, TXNRD2 F10 551/4885PTPN1 3492/4885PTPN2 2958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.